Cytochrome P450

Cat. No.

A10225

CAS No.

81103-11-9

Clarithromycin

Synonyms: A-56268

Clarithromycin is a macrolide antibiotic. It prevents bacteria from growing by interfering with their protein synthesis.

Cat. No.

A10054

CAS No.

72-48-0

Alizarin

Synonyms: Rubia; alizarin crimson; crimson madder; rose madder

Alizarin is novelly used as a staining agent in biological research because it stains free calcium and certain calcium compounds a red or light purple color.

Cat. No.

A10020

CAS No.

154229-19-3

Abiraterone (CB-7598)

Synonyms: CB-7598

Abiraterone (CB-7598) inhibits 17 α-hydroxylase/C17,20 lyase (CYP17A1), an enzyme which is expressed in testicular, adrenal, and prostatic tumor tissues.

Cat. No.

A10102

CAS No.

166518-60-1

Avasimibe (CI-1011)

Synonyms: PD 148515; CI-1011

Avasimibe (CI-1011) is an orally bioavailable Acyl-CoA:Cholesterol O-Acyltransferase (ACAT) inhibitor.

Cat. No.

A10120

CAS No.

491-67-8

Baicalein

Baicalein is a flavonoid originally isolated from the roots of Scutellaria baicalensis Georgi. Baicalein inhibits lipid peroxidation, as assessed by production of TBARS, with an IC50 value of 5 µM.

Cat. No.

A10489

CAS No.

84625-61-6

Itraconazole

Synonyms: Sporanox

Itraconazole is a relatively potent inhibitor of CYP3A4 with IC50 of 6.1 nM, used as a triazole antifungal agent.

Cat. No.

A10267

CAS No.

1155360-99-8

Cytochrome P450 14a-demethylase inhibitor 1a

Cat. No.

A10268

CAS No.

1155361-00-4

Cytochrome P450 14a-demethylase inhibitor 1b

Cat. No.

A10269

CAS No.

1155361-01-5

Cytochrome P450 14a-demethylase inhibitor 1c

Cat. No.

A10270

CAS No.

1155361-02-6

Cytochrome P450 14a-demethylase inhibitor 1d

Cat. No.

A10271

CAS No.

1155361-03-7

Cytochrome P450 14a-demethylase inhibitor 1e

Cat. No.

A10272

CAS No.

1155361-04-8

Cytochrome P450 14a-demethylase inhibitor 1f

Cat. No.

A10273

CAS No.

1155361-05-9

Cytochrome P450 14a-demethylase inhibitor 1g

Cat. No.

A10274

CAS No.

1155361-06-0

Cytochrome P450 14a-demethylase inhibitor 1h

Cat. No.

A10275

CAS No.

1155361-07-1

Cytochrome P450 14a-demethylase inhibitor 1i

Cat. No.

A10276

CAS No.

1155361-08-2

Cytochrome P450 14a-demethylase inhibitor 1j

Cat. No.

A10277

CAS No.

1155361-09-3

Cytochrome P450 14a-demethylase inhibitor 1k

Cat. No.

A10278

CAS No.

1155361-10-6

Cytochrome P450 14a-demethylase inhibitor 1L

Cat. No.

A10279

CAS No.

1155361-11-7

Cytochrome P450 14a-demethylase inhibitor 1m

Cat. No.

A10280

CAS No.

1155361-12-8

Cytochrome P450 14a-demethylase inhibitor 1n

Cat. No.

A10446

CAS No.

52-86-8

Haloperidol

Synonyms: Haldol

Haloperidol (Haldol) is an antipsychotic and butyrophenone.

Cat. No.

A10498

CAS No.

65277-42-1

Ketoconazole

Synonyms: Nizoral; Extina; Xolegel; Kuric

As an antifungal, ketoconazole is structurally similar to imidazole, and interferes with the fungal synthesis of ergosterol, a constituent of fungal cell membranes, as well as certain enzymes.

Cat. No.

A10578

CAS No.

298-81-7

Methoxsalen

Synonyms: Xanthotoxin; Metoxaleno; Dltasoralen; Meladinine; Uvadex; Oxsoralen

Methoxsalen (8-Methoxypsoralen) is a potent tricyclic furocoumarin suicide inhibitor of CYP (cytochrome P-450).

Cat. No.

A10688

CAS No.

82571-53-7

Ozagrel (OKY-046)

Synonyms: OKY-046

Ozagrel is a potent and selective thromboxane A2 synthetase inhibitor with an IC50 of 4 nM.

Cat. No.

A10744

CAS No.

171228-49-2

Posaconazole

Synonyms: Noxafil

Posaconazole is an inhibitor primarily of CYP3A4, but it does not inhibit the activity of other CYP enzymes; Also an inhibitor of sterol C14α demethylase inhibitor with IC50 of 0.25 μM. Posaconazole has a median terminal elimination half-life of 15-35 hours.