Seviteronel

Catalog No.: A20996

CYP17 lyase inhibitor

Seviteronel

Seviteronel Chemical Structure

CAS NO. 1610537-15-9

Seviteronel (VT-464) is a potent CYP17 lyase inhibitor(h-Lyase IC50=69 nM) that demonstrated both exceptional in vitro lyase/hydroxylase selectivity (~10-fold) and oral activity in a hamster model of androgen biosynthesis inhibition.

Availability: In stock

Package Price Qty
5 mg
$378.00
10 mg
$651.00
50 mg
$1,932.00
100 mg
$3,864.00
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Biological Activity

Seviteronel (VT-464) is a potent CYP17 lyase inhibitor(h-Lyase IC50=69 nM) that demonstrated both exceptional in vitro lyase/hydroxylase selectivity (~10-fold) and oral activity in a hamster model of androgen biosynthesis inhibition.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.04 mL 125.21 mL 250.41 mL
0.5 mM 5.01 mL 25.04 mL 50.08 mL
1 mM 2.5 mL 12.52 mL 25.04 mL
5 mM 0.5 mL 2.5 mL 5.01 mL

*The above data is based on the productmolecular weight 399.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A20996
Actions Inhibitor
M. Wt 399.34
Formula C18H17F4N3O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1610537-15-9
Synonyms VT-464, VT464, VT 464
SMILES FC(F)OC1=C(OC(F)F)C=C(C=CC([[email protected]](C2=CNN=N2)(C(C)C)O)=C3)C3=C1

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