Seviteronel

Catalog No.: A20996

CYP17 lyase inhibitor

Seviteronel

Seviteronel Chemical Structure

CAS NO. 1610537-15-9

Seviteronel (VT-464) is a potent CYP17 lyase inhibitor(h-Lyase IC50=69 nM) that demonstrated both exceptional in vitro lyase/hydroxylase selectivity (~10-fold) and oral activity in a hamster model of androgen biosynthesis inhibition.

Availability: In stock

Package Price Qty
5 mg
$378.00
10 mg
$651.00
50 mg
$1,932.00
100 mg
$3,864.00
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Seviteronel (VT-464) is a potent CYP17 lyase inhibitor(h-Lyase IC50=69 nM) that demonstrated both exceptional in vitro lyase/hydroxylase selectivity (~10-fold) and oral activity in a hamster model of androgen biosynthesis inhibition.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.04 mL 125.21 mL 250.41 mL
0.5 mM 5.01 mL 25.04 mL 50.08 mL
1 mM 2.5 mL 12.52 mL 25.04 mL
5 mM 0.5 mL 2.5 mL 5.01 mL

*The above data is based on the productmolecular weight 399.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A20996
Actions Inhibitor
CAS No. 1610537-15-9
Formula C18H17F4N3O3
M. Wt 399.34
Solubility DMSO
Purity >98%
Synonyms VT-464, VT464, VT 464
SMILES FC(F)OC1=C(OC(F)F)C=C(C=CC([[email protected]](C2=CNN=N2)(C(C)C)O)=C3)C3=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy Seviteronel | Seviteronel Supplier | purchase | cost | manufacturer | order | distributor | buy 1610537-15-9| 1610537-15-9 Supplier | purchase 1610537-15-9 | 1610537-15-9 cost | 1610537-15-9 manufacturer | order 1610537-15-9 | 1610537-15-9 distributor
Rewards