Apigenin

Catalog No.: A10081

Protein kinase inhibitor

Apigenin Chemical Structure

CAS NO. 520-36-5

Apigenin, found in many plants, is a natural product belonging to the flavone class that is the aglycone of several naturally-occurring glycosides. Apigenin acts as a monoamine transporter activator, one of the few chemicals demonstrated to possess this property. Apigenin is a ligand for central benzodiazepine receptors that competitively inhibited the binding of flunitrazepam with a Ki of 4μM, exerting anxiolytic and slight sedative effects.

Availability: In stock

Package Price Qty
50 mg

Regular Price: $60.00

Special Price $48.00

100 mg

Regular Price: $100.00

Special Price $80.00

200 mg

Regular Price: $150.00

Special Price $120.00

10mM * 1mL in DMSO
$62.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Apigenin, found in many plants, is a natural product belonging to the flavone class that is the aglycone of several naturally-occurring glycosides. Apigenin acts as a monoamine transporter activator, one of the few chemicals demonstrated to possess this property. Apigenin is a ligand for central benzodiazepine receptors that competitively inhibited the binding of flunitrazepam with a Ki of 4μM, exerting anxiolytic and slight sedative effects.

Targets
CYP2C9
2 μM(Ki)
In vitro DMSO 54 mg/mL (199.82 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 37.01 mL 185.05 mL 370.1 mL
0.5 mM 7.4 mL 37.01 mL 74.02 mL
1 mM 3.7 mL 18.5 mL 37.01 mL
5 mM 0.74 mL 3.7 mL 7.4 mL

*The above data is based on the productmolecular weight 270.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10081
Actions Inhibitor
M. Wt 270.2
Formula C15H10O5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 520-36-5
Synonyms 4’,5,7-trihydroxyflavone
SMILES C1=CC(=CC=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O

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