Biological Activity
Apigenin, found in many plants, is a natural product belonging to the flavone class that is the aglycone of several naturally-occurring glycosides. Apigenin acts as a monoamine transporter activator, one of the few chemicals demonstrated to possess this property. Apigenin is a ligand for central benzodiazepine receptors that competitively inhibited the binding of flunitrazepam with a Ki of 4μM, exerting anxiolytic and slight sedative effects.
Targets
CYP2C9 | ||||
2 μM(Ki) |
In vitro | DMSO | 54 mg/mL (199.82 mM) | |
Water | <1 mg/mL (<1 mM) | ||
Ethanol | <1 mg/mL (<1 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 37.01 mL | 185.05 mL | 370.1 mL |
0.5 mM | 7.4 mL | 37.01 mL | 74.02 mL |
1 mM | 3.7 mL | 18.5 mL | 37.01 mL |
5 mM | 0.74 mL | 3.7 mL | 7.4 mL |
*The above data is based on the productmolecular weight 270.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A10081 |
---|---|
Actions | Inhibitor |
M. Wt | 270.2 |
Formula | C15H10O5 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 520-36-5 |
Synonyms | 4’,5,7-trihydroxyflavone |
SMILES | C1=CC(=CC=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O |
Product Tags
Product Questions
Product Questions
No Questions
Keywords:buy Apigenin | Apigenin Supplier | purchase | cost | manufacturer | order | distributor | buy 520-36-5| 520-36-5 Supplier | purchase 520-36-5 | 520-36-5 cost | 520-36-5 manufacturer | order 520-36-5 | 520-36-5 distributor