TAK-700 Salt (Orteronel Salt)

Catalog No.: A13515

CYP17A1/androgen synthesis inhibitor

TAK-700 Salt (Orteronel Salt)

TAK-700 Salt (Orteronel Salt) Chemical Structure

CAS NO. 426219-53-6

Orteronel (TAK700) is an androgen synthesis inhibitor. It selectively inhibits the enzyme CYP17A which is expressed in testicular, adrenal, and prostatic tumor tissues.

Availability: In stock

Package Price Qty
5 mg
$120.00
10 mg
$200.00
25 mg
$400.00
50 mg
$700.00
10mM * 1mL in DMSO
$251.00
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Biological Activity

Orteronel (TAK700) is an androgen synthesis inhibitor. It selectively inhibits the enzyme CYP17A which is expressed in testicular, adrenal, and prostatic tumor tissues.
In vitro (25°C) DMSO 57 mg/mL (185.46 mM)
Water Insoluble
Ethanol 8 mg/mL
In vivo 0.5% methylcellulose 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.78 mL 93.89 mL 187.78 mL
0.5 mM 3.76 mL 18.78 mL 37.56 mL
1 mM 1.88 mL 9.39 mL 18.78 mL
5 mM 0.38 mL 1.88 mL 3.76 mL

*The above data is based on the productmolecular weight 532.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13515
Actions Inhibitor
CAS No. 426219-53-6
Formula C28H28N4O7
M. Wt 532.54
Purity >98%
Synonyms TAK 700, TAK700
SMILES CNC(=O)C1=CC2=C(C=C1)C=C(C=C2)C3(CCN4C3=CN=C4)O.C1=CC=C(C=C1)NC(=O)[[email protected]]([[email protected]@H](C(=O)O)O)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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