Biological Activity
Abiraterone (CB-7598) inhibits 17 α-hydroxylase/C17,20 lyase (CYP17A1), an enzyme which is expressed in testicular, adrenal, and prostatic tumor tissues.
Targets
CYP17 (Cell-free assay) | ||||
2 nM |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 28.64 mL | 143.18 mL | 286.37 mL |
0.5 mM | 5.73 mL | 28.64 mL | 57.27 mL |
1 mM | 2.86 mL | 14.32 mL | 28.64 mL |
5 mM | 0.57 mL | 2.86 mL | 5.73 mL |
*The above data is based on the productmolecular weight 349.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A10020 |
---|---|
Actions | Inhibitor |
CAS No. | 154229-19-3 |
Formula | C24H31NO |
M. Wt | 349.2 |
Purity | >98% |
Synonyms | CB-7598, CB7598 |
SMILES | C[[email protected]]12CC[[email protected]@H](CC1=CC[[email protected]@H]3[[email protected]@H]2CC[[email protected]]4([[email protected]]3CC=C4C5=CN=CC=C5)C)O |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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