Abiraterone (CB-7598)

Catalog No.: A10020

CYP17 inhibitor

Abiraterone (CB-7598)

Abiraterone (CB-7598) Chemical Structure

CAS NO. 154229-19-3

Abiraterone (CB-7598) inhibits 17 α-hydroxylase/C17,20 lyase (CYP17A1), an enzyme which is expressed in testicular, adrenal, and prostatic tumor tissues.

Availability: In stock

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5 mg

Regular Price: $40.00

Special Price $32.00

10 mg

Regular Price: $50.00

Special Price $40.00

50 mg

Regular Price: $60.00

Special Price $48.00

100 mg

Regular Price: $80.00

Special Price $64.00

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Biological Activity

Abiraterone (CB-7598) inhibits 17 α-hydroxylase/C17,20 lyase (CYP17A1), an enzyme which is expressed in testicular, adrenal, and prostatic tumor tissues.
Targets
CYP17 (Cell-free assay)
2 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.64 mL 143.18 mL 286.37 mL
0.5 mM 5.73 mL 28.64 mL 57.27 mL
1 mM 2.86 mL 14.32 mL 28.64 mL
5 mM 0.57 mL 2.86 mL 5.73 mL

*The above data is based on the productmolecular weight 349.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10020
Actions Inhibitor
CAS No. 154229-19-3
Formula C24H31NO
M. Wt 349.2
Purity >98%
Synonyms CB-7598, CB7598
SMILES C[[email protected]]12CC[[email protected]@H](CC1=CC[[email protected]@H]3[[email protected]@H]2CC[[email protected]]4([[email protected]]3CC=C4C5=CN=CC=C5)C)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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