Fig. 1 · Structure
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epi-D-Captopril
Cat. No.
A50632
CAS
112243-88-6
Metallo-β-lactamases (MBLs) Inhibitor
epi-D-Captopril is a stereoisomer of Captopril that serves as an inhibitor of metallo-β-lactamases (MBLs). It demonstrates inhibitory activity with IC50 values against NDM-1, IMP-1, and VIM-2 of 64 μM, 173 μM, and 5.5 μM, respectively. This reagent is useful for research applications focused on understanding and addressing drug-resistant bacterial infections associated with MBLs.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 112243-88-6 |
| Applications | Metallo-β-lactamases (MBLs) Inhibitor |
| Formula | C9H15NO3S |
| Molecular Weight | 217.29 |
| Synonyms | epi-D-SQ 14225 |
| SMILES | SC[C@H](C)C(N1[C@H](CCC1)C(O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.