HeE1-2Tyr is a pyridobenzothiazole compound that serves as an inhibitor of RNA-dependent RNA polymerases (RdRp) in flavivirus. It demonstrates significant inhibitory activity against West Nile, Dengue, and SARS-CoV-2 RdRps, with an IC50 value of 27.6 μM in vitro. HeE1-2Tyr is valuable for research investigating viral replication and potential therapeutic strategies targeting RNA polymerase activity.
HeE1-2Tyr is a pyridobenzothiazole compound that serves as an inhibitor of RNA-dependent RNA polymerases (RdRp) in flavivirus. It demonstrates significant inhibitory activity against West Nile, Dengue, and SARS-CoV-2 RdRps, with an IC50 value of 27.6 μM in vitro. HeE1-2Tyr is valuable for research investigating viral replication and potential therapeutic strategies targeting RNA polymerase activity.
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