Loginx

If you have an account with us, please log in.

Create an AccountForgot Your Password?

* Required Fields

Create an Accountx

* Required Fields

Back to Login

Forgot Your Password?x

Please enter your email address below. You will receive a link to reset your password.

* Required Fields

Back to Login

Metabotropic glutamate receptors (mGluR)



12 Item(s)

per page

Set Descending Direction
Catalog No. Product Name Product Information
A11181

ADX-47273

ADX-47273 is a drug used in scientific research which acts as a positive allosteric modulator selective for the metabotropic glutamate receptor subtype mGluR5.

Learn More
A11126

BINA

BINA is a selective positive allosteric modulator of mGlu2 (EC50 = 33.2 nM in CHO cells expressing human mGlu2). Learn More
A11968

CTEP

CTEP is a highly potent, selective and orally bioavailable allosteric antagonist of mGlu5 receptor with an IC50 of 2.2 nM. Learn More
A13123

LY 379268

LY 379268 is a highly selective group II mGlu receptor agonist (EC50 values are 2.69 and 4.48 nM for hmGlu2 and hmGlu3 respectively) that displays > 80-fold selectivity over group I and group III receptors. Learn More
A10544

LY2140023 (LY404039)

LY-404039 is a drug used in scientific research that acts as a selective agonist for the metabotropic glutamate receptor group II subtypes mGluR2 and mGluR3. It has anxiolytic and antipsychotic effects in animal studies, but without causing sedation. Early human trials using a prodrug form of LY-404,039 called LY-214,0023 have also given encouraging results. Learn More
A12589

MPEP hydrochloride

MPEP hydrochloride is a potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. Learn More
A12705

PHCCC

PHCCC is a group I metabotropic glutamate receptor antagonist (IC50 ~ 3 μM). Learn More
A13758

SIB 1757

SIB 1757 is a highly selective antagonist for the mGlu5 metabotropic glutamate receptor subtype. Learn More
A13759

SIB 1893

SIB 1893 is a highly selective non-competitive antagonist for the metabotropic glutamate mGlu5 receptor subtype. Learn More
A11754

VU 0357121

VU 0357121 is a positive allosteric modulator (PAM) of the metabotropic glutamate receptor 5 (mGlu5) with EC50 = 33 nM, 92% Glumax. Learn More
A12467

VU 0361737

VU 0361737 is a selective positive allosteric modulator at mGluR-4 (EC50 values are 240 and 110 nM at human and rat receptors respectively). Learn More
A12664

VU 0364439

VU 0364439 is a positive allosteric modulator (PAM) of mGlu4 receptors (EC50 = 19.8 nM in vitro for human mGlu4). Learn More

12 Item(s)

per page

Set Descending Direction
Metabotropic glutamate receptors (mGluR)

Minimal Price: $40.00