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Biological Activity
LY 379268 is a highly selective group II mGlu receptor agonist (EC50 values are 2.69 and 4.48 nM for hmGlu2 and hmGlu3 respectively) that displays > 80-fold selectivity over group I and group III receptors.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 53.43 mL | 267.17 mL | 534.33 mL |
| 0.5 mM | 10.69 mL | 53.43 mL | 106.87 mL |
| 1 mM | 5.34 mL | 26.72 mL | 53.43 mL |
| 5 mM | 1.07 mL | 5.34 mL | 10.69 mL |
*The above data is based on the productmolecular weight 187.15. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13123 |
|---|---|
| Actions | Agonist |
| CAS No. | 191471-52-0 |
| Formula | C7H9NO5 |
| M. Wt | 187.15 |
| Purity | >98% |
| Synonyms | LY379268, LY-379268 |
| SMILES | C1[[email protected]]([[email protected]@H]2[[email protected]]([[email protected]@H]2O1)C(=O)O)(C(=O)O)N |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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