Biological Activity
BMT-145027 is an mGluR5 positive allosteric modulator without inherent agonist activity, exhibits an EC50 of 47 nM.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 22.79 mL | 113.94 mL | 227.88 mL |
0.5 mM | 4.56 mL | 22.79 mL | 45.58 mL |
1 mM | 2.28 mL | 11.39 mL | 22.79 mL |
5 mM | 0.46 mL | 2.28 mL | 4.56 mL |
*The above data is based on the productmolecular weight 438.83. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A12457 |
---|---|
Actions | Modulator |
CAS No. | 2018282-44-3 |
Formula | C23H14ClF3N4 |
M. Wt | 438.83 |
Purity | >98% |
Synonyms | BMT145027, BMT 145027 |
SMILES | ClC(C(C(F)(F)F)=C1)=CC=C1C2=NNC3=NC(C4=CC=CC=C4)=C(C#N)C(C5CC5)=C32 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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