BMT-145027

Catalog No.: A12457

mGluR5 positive allosteric modulator

BMT-145027

BMT-145027 Chemical Structure

CAS NO. 2018282-44-3

BMT-145027 is an mGluR5 positive allosteric modulator without inherent agonist activity, exhibits an EC50 of 47 nM.

Availability: In stock

Package Price Qty
1 mg
$81.00
5 mg
$243.00
10 mg
$414.00
50 mg
$1,242.00
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Biological Activity

BMT-145027 is an mGluR5 positive allosteric modulator without inherent agonist activity, exhibits an EC50 of 47 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.79 mL 113.94 mL 227.88 mL
0.5 mM 4.56 mL 22.79 mL 45.58 mL
1 mM 2.28 mL 11.39 mL 22.79 mL
5 mM 0.46 mL 2.28 mL 4.56 mL

*The above data is based on the productmolecular weight 438.83. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12457
Actions Modulator
CAS No. 2018282-44-3
Formula C23H14ClF3N4
M. Wt 438.83
Purity >98%
Synonyms BMT145027, BMT 145027
SMILES ClC(C(C(F)(F)F)=C1)=CC=C1C2=NNC3=NC(C4=CC=CC=C4)=C(C#N)C(C5CC5)=C32
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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