JNJ 42153605

Catalog No.: A14330
mGluR-2 modulator
JNJ-42153605 is a positive allosteric modulator of the metabotropic glutamate 2 receptor.
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JNJ 42153605 5mg
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JNJ 42153605 10mg
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Biological Activity
Discription JNJ-42153605 is a positive allosteric modulator of the metabotropic glutamate 2 receptor.
Target Value
Product Information
Catalog Num A14330
Formula C22H23F3N4
Molecular Weight 400.187
CAS Number 1254977-87-1
SMILES FC(c1c(ccn2c1nnc2CC1CC1)N1CCC(CC1)c1ccccc1)(F)F
Synonyms JNJ-42153605, JNJ42153605

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

In vitro DMSO 4 mg/mL (9.98 mM)
Water Insoluble
Ethanol 10 mg/mL (24.97 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.99 mL 124.94 mL 249.88 mL
0.5 mM 5 mL 24.99 mL 49.98 mL
1 mM 2.5 mL 12.49 mL 24.99 mL
5 mM 0.5 mL 2.5 mL 5 mL
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