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Biological Activity
Basimglurant (RG7090) is a potent, selective and orally available mGlu5 negative allosteric modulator with a Kd of 1.1 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.7 mL | 153.48 mL | 306.97 mL |
| 0.5 mM | 6.14 mL | 30.7 mL | 61.39 mL |
| 1 mM | 3.07 mL | 15.35 mL | 30.7 mL |
| 5 mM | 0.61 mL | 3.07 mL | 6.14 mL |
*The above data is based on the productmolecular weight 325.77. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21225 |
|---|---|
| Actions | Modulator |
| CAS No. | 802906-73-6 |
| Formula | C18H13ClFN3 |
| M. Wt | 325.77 |
| Purity | >98% |
| Synonyms | RG7090, RG 7090, RG-7090; CTEP Derivative |
| SMILES | CC1=C(C#CC2=CC(Cl)=NC=C2)N=C(C)N1C3=CC=C(F)C=C3 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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