Auglurant

Catalog No.: A20958
mGlu5 antagonist
Auglurant (VU0424238) is a novel and selective mGlu5 antagonist with an IC50 value of 11 nM (rat) and an IC50 value of 14 nM (human). Auglurant (VU0424238) has an acceptable CNS penetration.
Grouped product items
Product Name Price Stock Qty
Auglurant 1mg
$320.00
In stock
Auglurant 5mg
$960.00
In stock
Auglurant 10mg
$1,600.00
In stock
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Biological Activity
Discription Auglurant (VU0424238) is a novel and selective mGlu5 antagonist with an IC50 value of 11 nM (rat) and an IC50 value of 14 nM (human). Auglurant (VU0424238) has an acceptable CNS penetration.
Targets
Target Value
Product Information
Catalog Num A20958
Formula C16H12FN5O2
Molecular Weight 325.3
CAS Number 1396337-04-4
SMILES CC1=NC(C(NC2=CC=C(F)C=N2)=O)=CC(OC3=CN=CN=C3)=C1
Synonyms VU0424238, VU 0424238, VU-0424238
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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