Auglurant

Name: Auglurant
Brand: Adooq Bioscience
SKU: A20958
Rating: 5 (288 reviews)

Catalog No.: A20958

mGlu5 antagonist

Auglurant (VU0424238) is a novel and selective mGlu5 antagonist with an IC50 value of 11 nM (rat) and an IC50 value of 14 nM (human). Auglurant (VU0424238) has an acceptable CNS penetration.

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Grouped product items
Size	Price	Stock
1mg	$315.00	In stock
5mg	$440.00	In stock
10mg	$780.00	In stock
25mg	$1,425.00	In stock
50mg	$1,855.00	In stock
100mg	$2,495.00	In stock
*10mM 1mL in DMSO**	$425.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description

Auglurant (VU0424238) is a novel and selective mGlu5 antagonist with an IC50 value of 11 nM (rat) and an IC50 value of 14 nM (human). Auglurant (VU0424238) has an acceptable CNS penetration.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

Product Information

Catalog Num	A20958
Formula	C16H12FN5O2
Molecular Weight	325.3
CAS Number	1396337-04-4
SMILES	CC1=NC(C(NC2=CC=C(F)C=N2)=O)=CC(OC3=CN=CN=C3)=C1
Synonyms	VU0424238, VU 0424238, VU-0424238
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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