Auglurant

Catalog No.: A20958

mGlu5 antagonist

Auglurant

Auglurant Chemical Structure

CAS NO. 1396337-04-4

Auglurant (VU0424238) is a novel and selective mGlu5 antagonist with an IC50 value of 11 nM (rat) and an IC50 value of 14 nM (human). Auglurant (VU0424238) has an acceptable CNS penetration.

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Biological Activity

Auglurant (VU0424238) is a novel and selective mGlu5 antagonist with an IC50 value of 11 nM (rat) and an IC50 value of 14 nM (human). Auglurant (VU0424238) has an acceptable CNS penetration.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.74 mL 153.7 mL 307.41 mL
0.5 mM 6.15 mL 30.74 mL 61.48 mL
1 mM 3.07 mL 15.37 mL 30.74 mL
5 mM 0.61 mL 3.07 mL 6.15 mL

*The above data is based on the productmolecular weight 325.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A20958
Actions Antagonist
CAS No. 1396337-04-4
Formula C16H12FN5O2
M. Wt 325.3
Purity >98%
Synonyms VU0424238, VU 0424238, VU-0424238
SMILES CC1=NC(C(NC2=CC=C(F)C=N2)=O)=CC(OC3=CN=CN=C3)=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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