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Biological Activity
VU6001376 is a potent and selective positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu4 PAM) with an EC50 of 50.1 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.97 mL | 124.87 mL | 249.74 mL |
| 0.5 mM | 4.99 mL | 24.97 mL | 49.95 mL |
| 1 mM | 2.5 mL | 12.49 mL | 24.97 mL |
| 5 mM | 0.5 mL | 2.5 mL | 4.99 mL |
*The above data is based on the productmolecular weight 400.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13763 |
|---|---|
| Actions | Modulator |
| CAS No. | 1968546-34-0 |
| Formula | C18H14F2N6OS |
| M. Wt | 400.41 |
| Purity | >98% |
| Synonyms | VU 6001376, VU-6001376 |
| SMILES | O=C(NC1CC(F)(F)C1)C2=NSC3=CC(NC4=NNC5=C4N=CC=C5)=CC=C32 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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Contact information
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