MPEP

Catalog No.: A12589
mGlu5 receptor antagonist
MPEP is a potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors.
Grouped product items
Product Name Price Stock Qty
MPEP 10mg
$50.00
In stock
MPEP 25mg
$100.00
In stock
MPEP 50mg
$160.00
In stock
MPEP 100mg
$280.00
In stock
MPEP 10mM * 1mL in DMSO
$70.00
In stock
Bulk Size
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Biological Activity
Discription MPEP is a potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors.
Targets
Target Value
Product Information
Catalog Num A12589
Formula C14H11N
Molecular Weight 193.249
CAS Number 96206-92-7
SMILES CC1=CC=CC(=N1)C#CC2=CC=CC=C2
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 36 mg/mL (186.3 mM)
Water Insoluble
Ethanol 36 mg/mL (186.3 mM)
In vivo 2% DMSO+30% PEG 300+5% Tween 80 9 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 51.75 mL 258.73 mL 517.47 mL
0.5 mM 10.35 mL 51.75 mL 103.49 mL
1 mM 5.17 mL 25.87 mL 51.75 mL
5 mM 1.03 mL 5.17 mL 10.35 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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