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Biological Activity
Lu AF21934 is a selective and brain-penetrant mGlu4 receptor positive allosteric modulator with an IC50 of 500 nM for human mGlu4.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.73 mL | 158.63 mL | 317.26 mL |
| 0.5 mM | 6.35 mL | 31.73 mL | 63.45 mL |
| 1 mM | 3.17 mL | 15.86 mL | 31.73 mL |
| 5 mM | 0.63 mL | 3.17 mL | 6.35 mL |
*The above data is based on the productmolecular weight 315.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12140 |
|---|---|
| Actions | Modulator |
| CAS No. | 1445605-23-1 |
| Formula | C14H16Cl2N2O2 |
| M. Wt | 315.2 |
| Purity | >98% |
| Synonyms | Lu-AF21934, LuAF21934, Lu AF-21934 |
| SMILES | O=C([[email protected]@H]1[[email protected]](C(N)=O)CCCC1)NC2=CC=C(Cl)C(Cl)=C2 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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