Lu AF21934

Catalog No.: A12140

mGlu4 receptor modulator

Lu AF21934

Lu AF21934 Chemical Structure

CAS NO. 1445605-23-1

Lu AF21934 is a selective and brain-penetrant mGlu4 receptor positive allosteric modulator with an IC50 of 500 nM for human mGlu4.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $68.00

Special Price $54.40

10 mg

Regular Price: $116.00

Special Price $92.80

50 mg

Regular Price: $345.00

Special Price $276.00

100 mg

Regular Price: $690.00

Special Price $552.00

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Biological Activity

Lu AF21934 is a selective and brain-penetrant mGlu4 receptor positive allosteric modulator with an IC50 of 500 nM for human mGlu4.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.73 mL 158.63 mL 317.26 mL
0.5 mM 6.35 mL 31.73 mL 63.45 mL
1 mM 3.17 mL 15.86 mL 31.73 mL
5 mM 0.63 mL 3.17 mL 6.35 mL

*The above data is based on the productmolecular weight 315.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12140
Actions Modulator
CAS No. 1445605-23-1
Formula C14H16Cl2N2O2
M. Wt 315.2
Purity >98%
Synonyms Lu-AF21934, LuAF21934, Lu AF-21934
SMILES O=C([[email protected]@H]1[[email protected]](C(N)=O)CCCC1)NC2=CC=C(Cl)C(Cl)=C2
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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