Fig. 1 · Structure

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SIB 1757

Cat. No. A13758 CAS 31993-01-8

mGluR antagonist

SIB 1757 is a highly selective antagonist for the mGlu5 metabotropic glutamate receptor subtype.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 31993-01-8
Applications mGluR antagonist
Formula C12H11N3O
Molecular Weight 213.24
SMILES
CC1=N/C(=N\NC2=CC=CC=C2)/C(=O)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

SolventReported Solubility
DMSO 22 mg/mL (103.17 mM)
Water Insoluble
Ethanol 9 mg/mL (42.2 mM)

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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