Mavoglurant

Catalog No.: A21223

mGlu5 receptor antagonist

Mavoglurant

Mavoglurant Chemical Structure

CAS NO. 543906-09-8

Mavoglurant is a structurally novel, non-competitive mGlu5 receptor antagonist, has an IC50 of 30 nM in a functional assay with human mGluR5.

Availability: In stock

Package Price Qty
5 mg
$378.00
10 mg
$651.00
50 mg
$1,932.00
100 mg
$3,864.00
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Biological Activity

Mavoglurant is a structurally novel, non-competitive mGlu5 receptor antagonist, has an IC50 of 30 nM in a functional assay with human mGluR5.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.91 mL 159.55 mL 319.09 mL
0.5 mM 6.38 mL 31.91 mL 63.82 mL
1 mM 3.19 mL 15.95 mL 31.91 mL
5 mM 0.64 mL 3.19 mL 6.38 mL

*The above data is based on the productmolecular weight 313.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21223
Actions Antagonist
CAS No. 543906-09-8
Formula C19H23NO3
M. Wt 313.39
Purity >98%
Synonyms AFQ056, AFQ 056, AFQ-056
SMILES CC1=CC(C#C[[email protected]]2(O)CCC[[email protected]]3([H])[[email protected]@]2([H])CCN3C(OC)=O)=CC=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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