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Mavoglurant is a structurally novel, non-competitive mGlu5 receptor antagonist, has an IC50 of 30 nM in a functional assay with human mGluR5.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.91 mL | 159.55 mL | 319.09 mL |
| 0.5 mM | 6.38 mL | 31.91 mL | 63.82 mL |
| 1 mM | 3.19 mL | 15.95 mL | 31.91 mL |
| 5 mM | 0.64 mL | 3.19 mL | 6.38 mL |
*The above data is based on the productmolecular weight 313.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21223 |
|---|---|
| Actions | Antagonist |
| M. Wt | 313.39 |
| Formula | C19H23NO3 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 543906-09-8 |
| Synonyms | AFQ056, AFQ 056, AFQ-056 |
| SMILES | CC1=CC(C#C[[email protected]]2(O)CCC[[email protected]]3([H])[[email protected]@]2([H])CCN3C(OC)=O)=CC=C1 |
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