IDO

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  1. IACS-8968 S-enantiomer

    Catalog No. A21559
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    dual IDO/TDO inhibitor
    IACS-8968 (S-enantiomer) is the S-enantiomer of IACS-8968. IACS-8968 is a dual IDO and TDO inhibitor, with pIC50s of 6.43 for IDO and <5 for TDO, respectively. Learn More
  2. IACS-8968 R-enantiomer

    Catalog No. A21555
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    dual IDO/TDO inhibitor
    IACS-8968 (R-enantiomer) is the R-enantiomer of IACS-8968. IACS-8968 is a dual IDO and TDO inhibitor, with pIC50s of 6.43 for IDO and <5 for TDO, respectively. Learn More
  3. IDO-IN-4

    Catalog No. A21077
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    IDO-1 inhibitor
    IDO-IN-4 is an indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor, extracted from patent WO2014150677A1, Compound example 1 enantiomer 1. Learn More
  4. IDO-IN-5

    Catalog No. A21074
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    IDO inhibitor
    IDO-IN-5 (NLG-1489) is an indoleamine 2,3-dioxygenase (IDO) inhibitor extracted from patent WO WO2012142237A1, compound 1489, has an IC50 of 1-10 μM. Learn More
  5. IDO-IN-3

    Catalog No. A20898
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    IDO inhibitor
    IDO-IN-3 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 290 nM. Learn More
  6. GNF-PF-3777

    Catalog No. A13507
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    hIDO2 inhibitor
    GNF-PF-3777 (8-Nitrotryptanthrin) is a potent human indoleamine 2,3-dioxygenase 2 (hIDO2) inhibitor which significantly reduces IDO2 activity with Ki of 0.97 μM. Learn More
  7. IDO-IN-12

    Catalog No. A18988
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    IDO inhibitor
    IDO-IN-12 is an indoleamine 2,3-dioxygenase (IDO) inhibitor extracted from patent WO 2017181849 A1. Learn More
  8. IDO/TDO-IN-1

    Catalog No. A18566
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    IDO/TDO dual inhibitor
    IDO/TDO-IN-1 is a highly potent and orally active dual indoleamine-2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) inhibitor with IC50s of 9.7 and 47 nM, respectively . Learn More
  9. Epacadostat (INCB024360)

    Catalog No. A15554
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    IDO inhibitor
    Epacadostat is a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor with IC50 of 10 nM, Phase 2, Learn More
  10. BMS-986205

    Catalog No. A17013
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    IDO1 inhibitor
    BMS-986205, also known as Linrodostat, ONO-7701 and F001287, a potent and selective, orally active IDO1 inhibitor with potential immunomodulating and antineoplastic activities. CAS: 1923833-60-6 (free base) 2221034-29-1 (mesylate) Learn More
  11. NLG919

    Catalog No. A14322
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    IDO inhibitor
    NLG919 is an orally available inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), with potential immunomodulating and antineoplastic activities. Learn More
  12. Indoximod (NLG-8189)

    Catalog No. A14397
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    IDO inhibitor
    Indoximod is a methylated tryptophan with anti-immunosuppressive activity. Learn More
  13. INCB024360 analog

    Catalog No. A13004
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    IDO1 inhibitor
    INCB024360 is an orally available hydroxyamidine and inhibitor of indoleamine 2,3-dioxygenase (IDO1), with potential immunomodulating and antineoplastic activities. Learn More

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