Epacadostat (INCB024360)

Epacadostat is a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor with IC50 of 10 nM, Phase 2,
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5mg
$30.00
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10mg
$55.00
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25mg
$80.00
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50mg
$105.00
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100mg
$190.00
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200mg
$320.00
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500mg
$545.00
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1g
$790.00
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2g
$1,085.00
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10mM * 1mL in DMSO
$35.00
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Epacadostat (INCB024360) has been cited by 3 publications
  • Chunbo He, .et al. , Cancer Discov, 2024, Jan 12;14(1):176-193 PMID: 37931287
  • Saeko Yoshioka, .et al. , Int J Tryptophan Res, 2022, Nov 30;15 PMID: 36467776
  • Marta Galan-Diez, .et al. , Cancer Discov, 2022, Apr 1;12(4):1106-1127 PMID: 35046097
  • Biological Activity
    Discription Epacadostat is a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor with IC50 of 10 nM, Phase 2,
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    Product Information
    Catalog Num A15554
    Formula C11H13BrFN7O4S
    Molecular Weight 438.23
    CAS Number 1204669-58-8, 1204669-37-3
    SMILES C1=CC(=C(C=C1NC(=C2C(=NON2)NCCNS(=O)(=O)N)N=O)Br)F
    Synonyms INCB 024360
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 74 mg/mL (168.86 mM)
    Water Insoluble
    Ethanol Warmed: 45 mg/mL
    In vivo 5% DMSO+40% PEG 300+5% TWEEN 80+50 % ddH2O 4.13 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 22.82 mL 114.1 mL 228.19 mL
    0.5 mM 4.56 mL 22.82 mL 45.64 mL
    1 mM 2.28 mL 11.41 mL 22.82 mL
    5 mM 0.46 mL 2.28 mL 4.56 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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