Signaling Pathway
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| Discription | Epacadostat is a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor with IC50 of 10 nM, Phase 2, | |||||
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| Cell Research |
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| Catalog Num | A15554 |
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| Formula | C11H13BrFN7O4S |
| Molecular Weight | 438.23 |
| CAS Number | 1204669-58-8, 1204669-37-3 |
| SMILES | C1=CC(=C(C=C1NC(=C2C(=NON2)NCCNS(=O)(=O)N)N=O)Br)F |
| Synonyms | INCB 024360 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | 74 mg/mL (168.86 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 45 mg/mL | ||
| In vivo | 5% DMSO+40% PEG 300+5% TWEEN 80+50 % ddH2O | 4.13 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.82 mL | 114.1 mL | 228.19 mL |
| 0.5 mM | 4.56 mL | 22.82 mL | 45.64 mL |
| 1 mM | 2.28 mL | 11.41 mL | 22.82 mL |
| 5 mM | 0.46 mL | 2.28 mL | 4.56 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
