Epacadostat (INCB024360)

Epacadostat is a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor with IC50 of 10 nM, Phase 2,
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Product Name Price Stock Qty
Epacadostat (INCB024360) 5mg
$45.00
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Epacadostat (INCB024360) 10mg
$77.00
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Epacadostat (INCB024360) 25mg
$135.00
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Adooq Products cited in reputable paper
Adooq's Epacadostat (INCB024360) has been cited by 2 publications
  • Saeko Yoshioka, .et al. , Int J Tryptophan Res, 2022, Nov 30;15 PMID: 36467776
  • Marta Galan-Diez, .et al. , Cancer Discov, 2022, Apr 1;12(4):1106-1127 PMID: 35046097
  • Biological Activity
    Discription Epacadostat is a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor with IC50 of 10 nM, Phase 2,
    Targets
    Target Value
    Product Information
    Catalog Num A15554
    Formula C11H13BrFN7O4S
    Molecular Weight 438.23
    CAS Number 1204669-58-8, 1204669-37-3
    SMILES C1=CC(=C(C=C1NC(=C2C(=NON2)NCCNS(=O)(=O)N)N=O)Br)F
    Synonyms INCB 024360
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 74 mg/mL (168.86 mM)
    Water Insoluble
    Ethanol Warmed: 45 mg/mL
    In vivo 5% DMSO+40% PEG 300+5% TWEEN 80+50 % ddH2O 4.13 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 22.82 mL 114.1 mL 228.19 mL
    0.5 mM 4.56 mL 22.82 mL 45.64 mL
    1 mM 2.28 mL 11.41 mL 22.82 mL
    5 mM 0.46 mL 2.28 mL 4.56 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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