ZC0109 is a potent dual inhibitor targeting indoleamine 2,3-dioxygenase 1 (IDO1) and thioredoxin reductase 1 (TrxR1), exhibiting IC50 values of 50 nM and 3.0 μM, respectively. This compound is effective in inducing reactive oxygen species (ROS) accumulation and causing cell cycle arrest at the G1/S phase, ultimately leading to apoptosis in cancer cells. ZC0109 is a valuable reagent for research applications focused on cancer therapy and the modulation of immune response through IDO1 and TrxR1 inhibition.
ZC0109 is a potent dual inhibitor targeting indoleamine 2,3-dioxygenase 1 (IDO1) and thioredoxin reductase 1 (TrxR1), exhibiting IC50 values of 50 nM and 3.0 μM, respectively. This compound is effective in inducing reactive oxygen species (ROS) accumulation and causing cell cycle arrest at the G1/S phase, ultimately leading to apoptosis in cancer cells. ZC0109 is a valuable reagent for research applications focused on cancer therapy and the modulation of immune response through IDO1 and TrxR1 inhibition.
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