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tert-Butyl (trans-3-formylcyclobutyl)carbamate

Catalog No.: A83966
PROTAC Linker
tert-Butyl (trans-3-formylcyclobutyl)carbamate is a novel PROTAC linker that facilitates the development of Proteolysis Targeting Chimeras (PROTACs). Its unique structure allows for efficient conjugation to E3 ligase ligands and target proteins, promoting targeted ubiquitination and subsequent degradation. This reagent is valuable for researchers investigating protein degradation pathways and therapeutic interventions in various diseases.
tert-Butyl (trans-3-formylcyclobutyl)carbamate 171549-92-1 PROTAC Linker
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptiontert-Butyl (trans-3-formylcyclobutyl)carbamate is a novel PROTAC linker that facilitates the development of Proteolysis Targeting Chimeras (PROTACs). Its unique structure allows for efficient conjugation to E3 ligase ligands and target proteins, promoting targeted ubiquitination and subsequent degradation. This reagent is valuable for researchers investigating protein degradation pathways and therapeutic interventions in various diseases.
Product Information
Catalog NumA83966
FormulaC10H17NO3
Molecular Weight199.25
CAS Number171549-92-1
SMILESN(C(OC(C)(C)C)=O)[C@@H]1C[C@@H](C=O)C1
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