Fig. 1 · Structure

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tert-Butyl (trans-3-formylcyclobutyl)carbamate

PROTAC Linker

tert-Butyl (trans-3-formylcyclobutyl)carbamate is a novel PROTAC linker that facilitates the development of Proteolysis Targeting Chimeras (PROTACs). Its unique structure allows for efficient conjugation to E3 ligase ligands and target proteins, promoting targeted ubiquitination and subsequent degradation. This reagent is valuable for researchers investigating protein degradation pathways and therapeutic interventions in various diseases.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 171549-92-1
Applications PROTAC Linker
Formula C10H17NO3
Molecular Weight 199.25
SMILES
N(C(OC(C)(C)C)=O)[C@@H]1C[C@@H](C=O)C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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