Fig. 1 · Structure

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Methyl (4-cyanophenyl)acetate

PROTAC Linker

Methyl (4-cyanophenyl)acetate serves as a valuable PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances the ability to recruit E3 ligases to target proteins, leading to their ubiquitination and subsequent degradation. Its role in PROTAC development is crucial for advancing studies in targeted protein modulation and exploring therapeutic applications in various disease models.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 52798-01-3
Applications PROTAC Linker
Formula C10H9NO2
Molecular Weight 175.19
SMILES
N#CC1=CC=C(C=C1)CC(=O)OC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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