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tert-Butyl 4-(4-(hydroxymethyl)phenoxy)piperidine-1-carboxylate

PROTAC Linker

tert-Butyl 4-(4-(hydroxymethyl)phenoxy)piperidine-1-carboxylate functions as a PROTAC linker, crucial for the development of proteolysis-targeting chimeras (PROTACs). This compound facilitates the conjugation of target proteins to E3 ligases, enabling targeted degradation in cellular systems. It is useful in studies of protein homeostasis, cellular signaling, and therapeutic applications in targeted protein degradation research.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	321337-38-6
Applications	PROTAC Linker
Formula	C₁₇H₂₅NO₄
Molecular Weight	307.39
SMILES	O=C(OC(C)(C)C)N1CCC(OC2=CC=C(C=C2)CO)CC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.