Fig. 1 · Structure
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12-Methoxy-12-oxododecanoic acid
PROTAC Linker
12-Methoxy-12-oxododecanoic acid functions as a versatile PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound is instrumental in connecting target ligands with E3 ligase recruiters, enhancing the degradation of specific proteins through the cellular ubiquitin-proteasome system. Its unique structure supports the efficient creation of PROTACs for use in various research applications, including studies on targeted protein degradation and the exploration of therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 3903-40-0 |
| Applications | PROTAC Linker |
| Formula | C13H24O4 |
| Molecular Weight | 244.33 |
| SMILES | O=C(O)CCCCCCCCCCC(=O)OC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.