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1-(2-Hydroxyethyl)piperidine-4-carbonitrile

PROTAC Linker

1-(2-Hydroxyethyl)piperidine-4-carbonitrile is a PROTAC linker that facilitates the development of proteolysis-targeting chimeras (PROTACs). It provides a flexible and efficient connection between E3 ligase recruiters and target proteins, enhancing the selective degradation of specific substrates. This compound is crucial for research applications focused on targeted protein degradation and the modulation of cellular pathways.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	21168-73-0
Applications	PROTAC Linker
Formula	C₈H₁₄N₂O
Molecular Weight	154.21
SMILES	N#CC1CCN(CCO)CC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.