N-(Mal-PEG6)-N-bis(PEG7-TCO) is a PEG-based linker specifically designed for PROTAC synthesis. This compound features a TCO moiety that facilitates the inverse electron demand Diels-Alder reaction (iEDDA) with tetrazine-containing molecules, enabling effective targeting and degradation of proteins. It is widely used in chemical biology to create novel therapeutics and to study protein interactions and degradation pathways.
N-(Mal-PEG6)-N-bis(PEG7-TCO) is a PEG-based linker specifically designed for PROTAC synthesis. This compound features a TCO moiety that facilitates the inverse electron demand Diels-Alder reaction (iEDDA) with tetrazine-containing molecules, enabling effective targeting and degradation of proteins. It is widely used in chemical biology to create novel therapeutics and to study protein interactions and degradation pathways.
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