Fig. 1 · Structure

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3-(2-Aminoethoxy)propan-1-ol hydrochloride

PROTAC Linker

3-(2-Aminoethoxy)propan-1-ol hydrochloride serves as a versatile PROTAC linker for the synthesis of proteolysis-targeting chimeras (PROTACs). It facilitates the conjugation of ligand and E3 ligase components, enhancing the generation of bifunctional molecules that mediate targeted protein degradation. This compound is applicable in drug discovery and development for studying protein turnover in various biological pathways.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 947664-36-0
Applications PROTAC Linker
Formula C5H14ClNO2
Molecular Weight 155.62
SMILES
Cl.OCCCOCCN

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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