Fig. 1 · Structure

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2-(4-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethyl)piperazin-1-yl)acetic acid dihydrochloride

PROTAC Linker

2-(4-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethyl)piperazin-1-yl)acetic acid dihydrochloride acts as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras. This compound plays a crucial role in the synthesis of PROTACs, enabling targeted protein degradation for various biological applications. Its unique structure allows for effective conjugation with target proteins, making it a valuable reagent in drug discovery and cellular biology research.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 204320-65-0
Applications PROTAC Linker
Formula C23H29Cl2N3O4
Molecular Weight 482.40
SMILES
O=C(NCCN1CCN(CC1)CC(O)=O)OCC2C3=C(C4=C2C=CC=C4)C=CC=C3.Cl.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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