Fig. 1 · Structure
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Hexane-1,6-diamine dihydrochloride
PROTAC Linker
Hexane-1,6-diamine dihydrochloride serves as a potent PROTAC linker, facilitating the construction of Proteolysis Targeting Chimeras (PROTACs). This compound enables effective recruitment of E3 ligases to target proteins for ubiquitination and subsequent degradation. Its application in the synthesis of PROTACs makes it a valuable tool for biochemical research, particularly in the study of protein regulation and therapeutic development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 6055-52-3 |
| Applications | PROTAC Linker |
| Formula | C6H18Cl2N2 |
| Molecular Weight | 189.13 |
| SMILES | NCCCCCCN.Cl.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.