Fig. 1 · Structure
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tert-Butyl 3-(4-aminophenyl)azetidine-1-carboxylate
PROTAC Linker
tert-Butyl 3-(4-aminophenyl)azetidine-1-carboxylate is a versatile PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the formation of bifunctional molecules that induce targeted protein degradation, providing a valuable tool for drug discovery and development. Its structural characteristics enhance the pharmacological properties of the resulting PROTACs, enabling researchers to explore novel therapeutic strategies in various biological contexts.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 916421-36-8 |
| Applications | PROTAC Linker |
| Formula | C14H20N2O2 |
| Molecular Weight | 248.33 |
| SMILES | O=C(OC(C)(C)C)N1CC(C2=CC=C(N)C=C2)C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.