Fig. 1 · Structure

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tert-Butyl 4-((2-hydroxyethoxy)methyl)piperidine-1-carboxylate

PROTAC Linker

tert-Butyl 4-((2-hydroxyethoxy)methyl)piperidine-1-carboxylate serves as a PROTAC linker facilitating the development of proteolysis-targeting chimeras. This compound is instrumental in connecting target proteins to E3 ligases, enabling selective degradation pathways in cellular research. Its chemical structure allows for enhanced solubility and stability, crucial for effective application in targeted protein degradation studies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1260099-72-6
Applications PROTAC Linker
Formula C13H25NO4
Molecular Weight 259.35
SMILES
O=C(OC(C)(C)C)N1CCC(COCCO)CC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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