NU 1025 is a potent poly(ADP-ribose) polymerase (PARP) inhibitor, which potentiates the cytotoxicity of a panel of mechanistically diverse anti-cancer agents in L1210 cells.
NU 1025 is a potent poly(ADP-ribose) polymerase (PARP) inhibitor, which potentiates the cytotoxicity of a panel of mechanistically diverse anti-cancer agents in L1210 cells.
Targets
Target
Value
Product Information
Catalog Num
A15375
Formula
C9H8N2O2
Molecular Weight
176.2
CAS Number
90417-38-2
SMILES
CC1=NC(=O)C2=C(N1)C(=CC=C2)O
Synonyms
NU1025, NU-1025
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Solubility
In vitro (25°C)
DMSO
34 mg/mL (192.99 mM)
Water
Insoluble
Ethanol
Warmed: 6 mg/mL
In vivo
40% PEG 400+saline
17 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
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