A-966492

Catalog No.: A10019

PARP1 inhibitor

A-966492

A-966492 Chemical Structure

CAS NO. 934162-61-5

A-966492 displayed high potency against the poly(ADP-ribose) polymerase-1 (PARP-1) enzyme with a K(i) of 1 nM and an EC(50) of 1 nM in a whole cell assay.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $90.00

Special Price $72.00

10 mg

Regular Price: $160.00

Special Price $128.00

50 mg

Regular Price: $450.00

Special Price $360.00

100 mg

Regular Price: $750.00

Special Price $600.00

10mM * 1mL in DMSO
$117.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

A-966492 displayed high potency against the poly(ADP-ribose) polymerase-1 (PARP-1) enzyme with a K(i) of 1 nM and an EC(50) of 1 nM in a whole cell assay.
Targets
PARP1 PARP1 PARP2
1 nM(Ki)1 nM(EC50)1.5 nM(Ki)
In vitro DMSO 65 mg/mL (200.4 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.83 mL 154.13 mL 308.26 mL
0.5 mM 6.17 mL 30.83 mL 61.65 mL
1 mM 3.08 mL 15.41 mL 30.83 mL
5 mM 0.62 mL 3.08 mL 6.17 mL

*The above data is based on the productmolecular weight 324.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A10019
Actions Inhibitor
M. Wt 324.4
Formula C18H17FN4O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 934162-61-5
Synonyms A966492
SMILES C1CC(NC1)C2=CC(=C(C=C2)C3=NC4=C(C=CC=C4N3)C(=O)N)F

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