A-966492

Catalog No.: A10019
PARP1 inhibitor
A-966492 displayed high potency against the poly(ADP-ribose) polymerase-1 (PARP-1) enzyme with a K(i) of 1 nM and an EC(50) of 1 nM in a whole cell assay.
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Product Name Price Stock Qty
A-966492 5mg
Special Price $72.00 Regular Price $90.00
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A-966492 10mg
Special Price $128.00 Regular Price $160.00
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A-966492 50mg
Special Price $360.00 Regular Price $450.00
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A-966492 100mg
Special Price $600.00 Regular Price $750.00
In stock
A-966492 10mM * 1mL in DMSO
Special Price $93.60 Regular Price $117.00
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Biological Activity
Discription A-966492 displayed high potency against the poly(ADP-ribose) polymerase-1 (PARP-1) enzyme with a K(i) of 1 nM and an EC(50) of 1 nM in a whole cell assay.
Targets
Target Value
Product Information
Catalog Num A10019
Formula C18H17FN4O
Molecular Weight 324.4
CAS Number 934162-61-5
SMILES C1CC(NC1)C2=CC(=C(C=C2)C3=NC4=C(C=CC=C4N3)C(=O)N)F
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO Warmed: 60 mg/mL (184.98 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.83 mL 154.13 mL 308.26 mL
0.5 mM 6.17 mL 30.83 mL 61.65 mL
1 mM 3.08 mL 15.41 mL 30.83 mL
5 mM 0.62 mL 3.08 mL 6.17 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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