A-966492

Catalog No.: A10019

PARP1 inhibitor

A-966492

A-966492 Chemical Structure

CAS NO. 934162-61-5

A-966492 displayed high potency against the poly(ADP-ribose) polymerase-1 (PARP-1) enzyme with a K(i) of 1 nM and an EC(50) of 1 nM in a whole cell assay.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $90.00

Special Price $72.00

10 mg

Regular Price: $160.00

Special Price $128.00

50 mg

Regular Price: $450.00

Special Price $360.00

100 mg

Regular Price: $750.00

Special Price $600.00

10mM * 1mL in DMSO

Regular Price: $117.00

Special Price $93.60

Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

A-966492 displayed high potency against the poly(ADP-ribose) polymerase-1 (PARP-1) enzyme with a K(i) of 1 nM and an EC(50) of 1 nM in a whole cell assay.
Targets
PARP1 PARP1 PARP2
1 nM(Ki)1 nM(EC50)1.5 nM(Ki)
In vitro DMSO Warmed: 60 mg/mL (184.98 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.83 mL 154.13 mL 308.26 mL
0.5 mM 6.17 mL 30.83 mL 61.65 mL
1 mM 3.08 mL 15.41 mL 30.83 mL
5 mM 0.62 mL 3.08 mL 6.17 mL

*The above data is based on the productmolecular weight 324.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10019
Actions Inhibitor
CAS No. 934162-61-5
Formula C18H17FN4O
M. Wt 324.4
Purity >98%
Synonyms A966492
SMILES C1CC(NC1)C2=CC(=C(C=C2)C3=NC4=C(C=CC=C4N3)C(=O)N)F
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
You may also be interested in the following product(s)
Keywords:buy A-966492 | A-966492 Supplier | purchase | cost | manufacturer | order | distributor | buy 934162-61-5| 934162-61-5 Supplier | purchase 934162-61-5 | 934162-61-5 cost | 934162-61-5 manufacturer | order 934162-61-5 | 934162-61-5 distributor
Rewards