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Catalog No.: A14309

PARP3 inhibitor


ME0328 Chemical Structure

CAS NO. 1445251-22-8

ME0328 is a potent and selective PARP inhibitor with IC50 of 0.89 μM for PARP3, about 7-fold selectivity over PARP1.

Availability: In stock

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25 mg
50 mg
100 mg
10mM * 1mL in DMSO
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Biological Activity

ME0328 is a potent and selective PARP inhibitor with IC50 of 0.89 μM for PARP3, about 7-fold selectivity over PARP1.
0.89 μM6.3 μM
In vitro DMSO 60 mg/mL (186.69 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.12 mL 155.58 mL 311.17 mL
0.5 mM 6.22 mL 31.12 mL 62.23 mL
1 mM 3.11 mL 15.56 mL 31.12 mL
5 mM 0.62 mL 3.11 mL 6.22 mL

*The above data is based on the productmolecular weight 321.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14309
Actions Inhibitor
CAS No. 1445251-22-8
Formula C19H19N3O2
M. Wt 321.37
Purity >98%
Synonyms ME 0328
SMILES C[[email protected]@H](C1=CC=CC=C1)NC(=O)CCC2=NC(=O)C3=CC=CC=C3N2

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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