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$0.00 - Jianwei Dou, .et al. Development and evaluation of poly adenosine 5'-diphosphate-ribose polymerase 1 immobilization-based receptor chromatography, J Sep Sci, 2020, Dec 4 PMID: 33275824
Biological Activity
Rucaparib is a potent inhibitor of purified full-length human PARP-1 and shows higher inhibition of cellular PARP in LoVo and SW620 cells.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.92 mL | 154.61 mL | 309.21 mL |
| 0.5 mM | 6.18 mL | 30.92 mL | 61.84 mL |
| 1 mM | 3.09 mL | 15.46 mL | 30.92 mL |
| 5 mM | 0.62 mL | 3.09 mL | 6.18 mL |
*The above data is based on the productmolecular weight 323.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A14182 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 283173-50-2 |
| Formula | C19H18FN3O |
| M. Wt | 323.4 |
| Purity | >98% |
| Synonyms | AG-014699,PF-01367338, AG 014699,PF 01367338, AG014699,PF01367338 |
| SMILES | CNCC1=CC=C(C=C1)C2=C3CCNC(=O)C4=CC(=CC(=C34)N2)F |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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