Rucaparib

Catalog No.: A14182

PARP-1 inhibitor

Rucaparib

Rucaparib Chemical Structure

CAS NO. 283173-50-2

Rucaparib is a potent inhibitor of purified full-length human PARP-1 and shows higher inhibition of cellular PARP in LoVo and SW620 cells.

Availability: In stock

Package Price Qty
5 mg
$60.00
10 mg
$100.00
25 mg
$200.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Jianwei Dou, .et al. Development and evaluation of poly adenosine 5'-diphosphate-ribose polymerase 1 immobilization-based receptor chromatography, J Sep Sci, 2020, Dec 4 PMID: 33275824

Biological Activity

Rucaparib is a potent inhibitor of purified full-length human PARP-1 and shows higher inhibition of cellular PARP in LoVo and SW620 cells.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.92 mL 154.61 mL 309.21 mL
0.5 mM 6.18 mL 30.92 mL 61.84 mL
1 mM 3.09 mL 15.46 mL 30.92 mL
5 mM 0.62 mL 3.09 mL 6.18 mL

*The above data is based on the productmolecular weight 323.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14182
Actions Inhibitor
CAS No. 283173-50-2
Formula C19H18FN3O
M. Wt 323.4
Purity >98%
Synonyms AG-014699,PF-01367338, AG 014699,PF 01367338, AG014699,PF01367338
SMILES CNCC1=CC=C(C=C1)C2=C3CCNC(=O)C4=CC(=CC(=C34)N2)F
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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