NMS-P118

Catalog No.: A20994

PARP-1 Inhibitor

NMS-P118

NMS-P118 Chemical Structure

CAS NO. 1262417-51-5

NMS-P118 is a potent, orally available, and highly selective PARP-1 Inhibitor for cancer therapy.

Availability: In stock

Package Price Qty
2 mg
$76.00
5 mg
$151.00
10 mg
$294.00
50 mg
$865.00
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Biological Activity

NMS-P118 is a potent, orally available, and highly selective PARP-1 Inhibitor for cancer therapy.
In vitro DMSO Warmed: 22 mg/mL (55.63 mM)
Water Insoluble
Ethanol Warmed: 5 mg/mL (12.64 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.29 mL 126.45 mL 252.9 mL
0.5 mM 5.06 mL 25.29 mL 50.58 mL
1 mM 2.53 mL 12.64 mL 25.29 mL
5 mM 0.51 mL 2.53 mL 5.06 mL

*The above data is based on the productmolecular weight 395.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A20994
Actions Inhibitor
CAS No. 1262417-51-5
Formula C20H24F3N3O2
M. Wt 395.42
Solubility DMSO
Purity >98%
Synonyms NMSP118, NMS P118, NMS-P-118
SMILES FC(CC1)(F)CCC1N(CC2)CCC2N(C3=O)CC4=C3C(C(N)=O)=CC(F)=C4
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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