UPF 1069 is a selective poly(ADP-ribose) polymerase (PARP) 2 inhibitor (IC50 values are 0.3 and 8.0 μM for PARP-2 and PARP-1 respectively).
Targets
Target
Value
Product Information
Catalog Num
A12750
Formula
C17H13NO3
Molecular Weight
279.29
CAS Number
1048371-03-4
SMILES
C1=CC=C(C=C1)C(=O)COC2=CC=CC3=C2C=CNC3=O
Synonyms
UPF1069, UPF-1069
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Solubility
In vitro (25°C)
DMSO
54 mg/mL (193.34 mM)
Water
Insoluble
Ethanol
Insoluble
In vivo
2% DMSO+30% PEG 300+5% Tween 80+ddH2O
4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
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