3-Aminobenzamide

Catalog No.: A10475

PARP Inhibitor

3-Aminobenzamide

3-Aminobenzamide Chemical Structure

CAS NO. 3544-24-9

3-Aminobenzamide is a novel PARP inhibitor, known to sensitize cells to radiation in vitro by inhibiting the repair of DNA damage.

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50 mg
$50.00
100 mg
$80.00
10mM * 1mL in DMSO
$55.00
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  • Kamada Y, .et al. Castalagin and vescalagin purified from leaves of Syzygium samarangense (Blume) Merrill & L.M. Perry: Dual inhibitory activity against PARP1 and DNA topoisomerase II, Fitoterapia, 2018, Sep;129:94-101 PMID: 29928967

Biological Activity

3-Aminobenzamide is a novel PARP inhibitor, known to sensitize cells to radiation in vitro by inhibiting the repair of DNA damage.
Targets
PARP
<50 nM
In vitro (25°C) DMSO 27 mg/mL (198.31 mM)
Water <1 mg/mL (<1 mM)
Ethanol 27 mg/mL (198.31 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 73.42 mL 367.11 mL 734.21 mL
0.5 mM 14.68 mL 73.42 mL 146.84 mL
1 mM 7.34 mL 36.71 mL 73.42 mL
5 mM 1.47 mL 7.34 mL 14.68 mL

*The above data is based on the productmolecular weight 136.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10475
Actions Inhibitor
M. Wt 136.2
Formula C7H8N2O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 3544-24-9
Synonyms 3-Aminobenzamide, 3-AB
SMILES C1=CC(=CC(=C1)N)C(=O)N

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