Olaparib (AZD2281)

Olaparib (AZD2281) is an inhibitor of poly ADP ribose polymerase (PARP), an enzyme involved in DNA repair.
Grouped product items
Product Name Price Stock Qty
Olaparib 10mg
Special Price $32.00 Regular Price $40.00
In stock
Olaparib 25mg
Special Price $48.00 Regular Price $60.00
In stock
Olaparib 50mg
Special Price $56.00 Regular Price $70.00
In stock
Olaparib 100mg
Special Price $72.00 Regular Price $90.00
In stock
Olaparib (AZD2281) 10mM * 1mL in DMSO
Special Price $60.80 Regular Price $76.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Not your Region? View all Distributors

Adooq Products cited in reputable paper
Adooq's Olaparib (AZD2281) has been cited by 28 publications
  • Saptarshi Sinha, .et al. , Exp Cell Res, 2022, Nov 1;420(1):113338 PMID: 36075449
  • Subhajit Chatterjee, .et al. , J Cancer Res Clin Oncol, 2022, Dec;148(12):3521-3535 PMID: 35962813
  • Yuki Uchihara, .et al. , Mol Cell, 2022, Jul 21;82(14):2557-2570 PMID: 35594857
  • Ji-Ye Kim, .et al. , Cell Death Dis, 2022, Mar 15;13(3):239 PMID: 35293383
  • Emad Matanes, .et al. , Front Oncol, 2021, Oct 27;11:745981 PMID: 34778062
  • Shino Endo, .et al. , Cancer Res Commun, 2021, 1(2): 90-105
  • Yan Baglo, .et al. , Transl Oncol, 2021, Nov;14(11):101198 PMID: 34418731
  • Joseph M Gozgit, .et al. , Cancer cell, 2021, Jul 22;S1535-6108(21)00340-8 PMID: 34375612
  • Sefinew Molla, .et al. , DNA Repair (Amst), 2021, Jun 10;105:103157 PMID: 34144488
  • Jianming Wang, .et al. , Cell Rep, 2021, Feb 16;34(7):108759 PMID: 33596418
  • Ai Ito, .et al. , Biogerontology, 2021, Feb;22(1):119-131 PMID: 33216250
  • Tim J Wigle, .et al. , Cell Chem Biol, 2020, Jul 16;27(7):877-887 PMID: 32679093
  • Ali Divan, .et al. , Pharmacol Res Perspect, 2020, Apr; 8(2): e00586 PMID: 32342655
  • Jianwei Dou, .et al. , J Sep Sci, 2020, Dec 4 PMID: 33275824
  • Sai Dimple Manavitha Gullipalli, .et al. , Int. J. Adv. Pharm. Biotech, 2020, 6(2) 01-08
  • Chao Zhang, .et al. , J Atheroscler Thromb, 2020, Sep 25 PMID: 32981917
  • Wigle TJ, .et al. , SLAS Discov, 2019, Dec 19:2472555219883623 PMID: 31855104
  • Wang Q, .et al. , Cancer Med, 2019, Dec 21 PMID: 31863638
  • Molla S, .et al. , Pathol Oncol Res, 2019, Nov 25 PMID: 31768967
  • Alvin Z.Lu, .et al. , Biochem Pharmacol, 2019, May 7. pii: S0006-2952(19)30171-6 PMID: 31075269
  • Bian C, .et al. , Nat Commun, 2019, Feb 11;10(1):693 PMID: 30741937
  • HC de Silva, .et al. , Cell Mol Life Sci, 2019, 1-16 PMID: 30725116
  • Kamada Y, .et al. , Fitoterapia, 2018, Sep;129:94-101 PMID: 29928967
  • 2018, .et al. , FEBS Open Bio, 2018, Jun; 8(6): 1001-1012 PMID: 29928579
  • Hirosumi Tamura, .et al. , Oncol Rep, 2018, Aug; 40(2): 635-646 PMID: 29917168
  • Hiro Sato, .et al. , Nat Commun, 2017, 8: 1751 PMID: 29170499
  • Charles-André Philip, .et al. , BMC Cancer, 2017, 17: 638 PMID: 28886696
  • Rulina AV, .et al. , Cell Death Dis, 2016, Dec 1;7(12):e2505 PMID: 27906189
  • Biological Activity
    Discription Olaparib (AZD2281) is an inhibitor of poly ADP ribose polymerase (PARP), an enzyme involved in DNA repair.
    Targets
    Target Value
    Product Information
    Catalog Num A10111
    Formula C24H23FN4O3
    Molecular Weight 434.5
    CAS Number 763113-22-0
    SMILES C1CC1C(=O)N2CCN(CC2)C(=O)C3=C(C=CC(=C3)CC4=NNC(=O)C5=CC=CC=C54)F
    Synonyms KU-0059436
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO Warmed: 74 mg/mL (170.32 mM)
    Water <1 mg/mL
    Ethanol Insoluble
    In vivo 4% DMSO+30% PEG 300+ddH2O 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 23.01 mL 115.07 mL 230.15 mL
    0.5 mM 4.6 mL 23.01 mL 46.03 mL
    1 mM 2.3 mL 11.51 mL 23.01 mL
    5 mM 0.46 mL 2.3 mL 4.6 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

    • Calculator Reset
    Keywords: buy Olaparib (AZD2281) | Olaparib (AZD2281) Supplier | purchase Olaparib (AZD2281) | Olaparib (AZD2281) cost | Olaparib (AZD2281) manufacturer | order Olaparib (AZD2281) | Olaparib (AZD2281) distributor | buy 763113-22-0 | 763113-22-0 Supplier | purchase 763113-22-0 | 763113-22-0 cost | 763113-22-0 manufacturer | order 763113-22-0 | 763113-22-0 distributor