XAV 939

Catalog No.: A10994
PARP inhibitor
XAV 939 is a TNKS inhibitor (IC50 values are 0.011 and 0.004 μM for TNKS1 and TNKS2 respectively).
Grouped product items
Product Name Price Stock Qty
XAV 939 10mg
$60.00
In stock
XAV 939 25mg
$120.00
In stock
XAV 939 50mg
$180.00
In stock
XAV 939 100mg
$280.00
In stock
XAV 939 10mM * 1mL in DMSO
$55.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's XAV 939 has been cited by 2 publications
  • Shizu Aikawa, .et al. , EMBO J, 2017, Jul 14; 36(14): 2146-2160 PMID: 28588064
  • Mikaël M. Martino, .et al. , Nat Commun, 2016, 7: 11051 PMID: 27001940
  • Biological Activity
    Discription XAV 939 is a TNKS inhibitor (IC50 values are 0.011 and 0.004 μM for TNKS1 and TNKS2 respectively).
    Targets
    Target Value
    Product Information
    Catalog Num A10994
    Formula C14H11F3N2OS
    Molecular Weight 312.3
    CAS Number 284028-89-3
    SMILES C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
    Synonyms XAV939, XAV-939
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 12 mg/mL (38.42 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 4% DMSO+corn oil 1 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 32.02 mL 160.1 mL 320.2 mL
    0.5 mM 6.4 mL 32.02 mL 64.04 mL
    1 mM 3.2 mL 16.01 mL 32.02 mL
    5 mM 0.64 mL 3.2 mL 6.4 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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