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XAV 939


PARP inhibitor

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Catalog No. A10994

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
XAV 939 10mg A10994-10

Regular Price: €57.00

Special Price: €51.30

XAV 939 25mg A10994-25

Regular Price: €114.00

Special Price: €102.60

XAV 939 50mg A10994-50

Regular Price: €171.00

Special Price: €153.90

XAV 939 100mg A10994-100

Regular Price: €266.00

Special Price: €239.40

XAV 939 10mM * 1mL in DMSO A10994-10mM-D

Regular Price: €52.25

Special Price: €47.03

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

XAV 939 is a TNKS inhibitor (IC50 values are 0.011 and 0.004 μM for TNKS1 and TNKS2 respectively).

XAV 939

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Publications citing Adooq Products
XAV 939 Citations (2)
  • Shizu Aikawa, .et al. Autotaxin-lysophosphatidic acid-LPA 3 signaling at the embryo-epithelial boundary controls decidualization pathways, EMBO J, 2017, Jul 14; 36(14): 2146-2160 PMID: 28588064
  • Mikaël M. Martino, .et al. Inhibition of IL-1R1/MyD88 signalling promotes mesenchymal stem cell-driven tissue regeneration, Nat Commun, 2016, 7: 11051 PMID: 27001940

Chemical Information

Catalog Num A10994
Actions Inhibitor
M. Wt 312.3
Formula C14H11F3N2OS
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 284028-89-3
Synonyms XAV939, XAV-939

Biological Activity

XAV 939 is a TNKS inhibitor (IC50 values are 0.011 and 0.004 μM for TNKS1 and TNKS2 respectively).
TNKS2 (Cell-free assay) TNKS1 (Cell-free assay)
4 nM11 nM


Solubility (25°C) * In vitro DMSO 12 mg/mL (38.42 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.02 mL 160.1 mL 320.2mL
0.5 mM 6.4 mL 32.02 mL 64.04 mL
1 mM 3.2 mL 16.01 mL 32.02 mL
5 mM 0.64 mL 3.2 mL 6.4 mL

*The above data is based on the productmolecular weight 312.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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