Biological Activity
BYK 49187, PARP-1 and PARP-2 inhibitor (pIC50 values are 8.36 and 7.50 for cell-free recombinant PARP-1 and murine PARP-2 respectively).
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 29.82 mL | 149.08 mL | 298.15 mL |
0.5 mM | 5.96 mL | 29.82 mL | 59.63 mL |
1 mM | 2.98 mL | 14.91 mL | 29.82 mL |
5 mM | 0.6 mL | 2.98 mL | 5.96 mL |
*The above data is based on the productmolecular weight 335.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A15372 |
---|---|
Actions | Inhibitor |
M. Wt | 335.4 |
Formula | C19H21N5O |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 163120-31-8 |
Synonyms | BYK49187, BYK-49187 |
SMILES | CC1=C(N=CN1)C2CCN(CC2)C3=NC4=CC=CC5=C4N3CCC5=O |
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