Niraparib hydrochloride

Catalog No.: A18018

PARP1 and PARP2 inhibitor

Niraparib hydrochloride

Niraparib hydrochloride Chemical Structure

CAS NO. 1038915-64-8

Niraparib hydrochloride (MK-4827 hydrochloride) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively.

Availability: In stock

Package Price Qty
5 mg
$97.00
10 mg
$167.00
50 mg
$497.00
100 mg
$994.00
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Biological Activity

Niraparib hydrochloride (MK-4827 hydrochloride) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.02 mL 140.11 mL 280.23 mL
0.5 mM 5.6 mL 28.02 mL 56.05 mL
1 mM 2.8 mL 14.01 mL 28.02 mL
5 mM 0.56 mL 2.8 mL 5.6 mL

*The above data is based on the productmolecular weight 356.85. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18018
Actions Inhibitor
M. Wt 356.85
Formula C19H21ClN4O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1038915-64-8
Synonyms MK-4827 hydrochloride, MK4827, MK 4827
SMILES NC(C1=CC=CC2=CN(C3=CC=C([[email protected]]4CNCCC4)C=C3)N=C21)=O.Cl

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