Pamiparib

Catalog No.: A17073

PARP inhibitor

Pamiparib

Pamiparib Chemical Structure

CAS NO. 1446261-44-4

Pamiparib, also known as BGB-290, is a highly potent and selective PARP inhibitor with favorable drug metabolism and pharmacokinetic properties. CAS: 1446261-44-1 (free base) 2086689-94-1 (maleate) 2086689-93-0 (hydrate)

Availability: In stock

Package Price Qty
5 mg
$160.00
10 mg
$260.00
50 mg
$920.00
100 mg
$1,400.00
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Biological Activity

Pamiparib, also known as BGB-290, is a highly potent and selective PARP inhibitor with favorable drug metabolism and pharmacokinetic properties. CAS: 1446261-44-1 (free base) 2086689-94-1 (maleate) 2086689-93-0 (hydrate)
In vitro DMSO 50 mg/mL (167.61 mM)
Water Insoluble
Ethanol 38 mg/mL (127.38 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.52 mL 167.61 mL 335.21 mL
0.5 mM 6.7 mL 33.52 mL 67.04 mL
1 mM 3.35 mL 16.76 mL 33.52 mL
5 mM 0.67 mL 3.35 mL 6.7 mL

*The above data is based on the productmolecular weight 298.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17073
Actions Inhibitor
CAS No. 1446261-44-4
Formula C16H15FN4O
M. Wt 298.32
Purity >98%
Synonyms BGB-290, BGB 290, BGB290
SMILES O=C1NN=C2CN(CCC3)[[email protected]@]3(C)C(N4)=C2C5=C4C=C(F)C=C51
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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