AG-014699 (Rucaparib)

Catalog No.: A10045

PARP inhibitor

AG-014699 (Rucaparib) Chemical Structure

CAS NO. 459868-92-9

AG-014699 (Rucaparib) is a PARP inhibitor that inhibits poly(ADP-ribose) polymerase (PARP) is a key enzyme in DNA repair.

Availability: In stock

Package Price Qty
5 mg
$60.00
25 mg
$220.00
50 mg
$270.00
100 mg
$422.00
10mM * 1mL in DMSO
$110.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

AG-014699 (Rucaparib) is a PARP inhibitor that inhibits poly(ADP-ribose) polymerase (PARP) is a key enzyme in DNA repair.
Targets
PARP (Cell-free assay)
1.4 nM(Ki)
In vitro (25°C) DMSO 84 mg/mL (199.35 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.73 mL 118.65 mL 237.3 mL
0.5 mM 4.75 mL 23.73 mL 47.46 mL
1 mM 2.37 mL 11.87 mL 23.73 mL
5 mM 0.47 mL 2.37 mL 4.75 mL

*The above data is based on the productmolecular weight 421.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10045
Actions Inhibitor
M. Wt 421.4
Formula C19H18FN3O.H3PO4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 459868-92-9
Synonyms AG014699, PF-01367338,AG-014447 (as free base)
SMILES CNCC1=CC=C(C=C1)C2=C3CCNC(=O)C4=CC(=CC(=C34)N2)F.OP(=O)(O)O

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy AG-014699 (Rucaparib) | AG-014699 (Rucaparib) Supplier | purchase AG-014699 (Rucaparib) | AG-014699 (Rucaparib) cost | AG-014699 (Rucaparib) manufacturer | order AG-014699 (Rucaparib) | AG-014699 (Rucaparib) distributor | buy 459868-92-9| 459868-92-9 Supplier | purchase 459868-92-9 | 459868-92-9 cost | 459868-92-9 manufacturer | order 459868-92-9 | 459868-92-9 distributor
Rewards