Total item
Cart Subtotal
$0.00 Customer Appreciation Sale.
15% off with promo code "APPRECIATION2023" on check out or purchase order
- Tahira Baloch, .et al. Sequential therapeutic targeting of ovarian Cancer harboring dysfunctional BRCA1, BMC Cancer, 2019, Jan 10;19(1):44 PMID: 30630446
Biological Activity
AG-014699 (Rucaparib) is a PARP inhibitor that inhibits poly(ADP-ribose) polymerase (PARP) is a key enzyme in DNA repair.
Targets
| PARP (Cell-free assay) | ||||
| 1.4 nM(Ki) |
| In vitro (25°C) | DMSO | 81 mg/mL (192.23 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 2% DMSO+30% PEG 300+2% Tween 80+ddH2O | 9 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.73 mL | 118.65 mL | 237.3 mL |
| 0.5 mM | 4.75 mL | 23.73 mL | 47.46 mL |
| 1 mM | 2.37 mL | 11.87 mL | 23.73 mL |
| 5 mM | 0.47 mL | 2.37 mL | 4.75 mL |
*The above data is based on the productmolecular weight 421.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10045 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 459868-92-9 |
| Formula | C19H18FN3O.H3PO4 |
| M. Wt | 421.4 |
| Purity | >98% |
| Synonyms | AG014699, PF-01367338,AG-014447 (as free base) |
| SMILES | CNCC1=CC=C(C=C1)C2=C3CCNC(=O)C4=CC(=CC(=C34)N2)F.OP(=O)(O)O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Datasheet
Product Tags
Product Questions
Product Questions
No Questions
Keywords:buy AG-014699 (Rucaparib) | AG-014699 (Rucaparib) Supplier | purchase | cost | manufacturer | order | distributor | buy 459868-92-9| 459868-92-9 Supplier | purchase 459868-92-9 | 459868-92-9 cost | 459868-92-9 manufacturer | order 459868-92-9 | 459868-92-9 distributor
Contact information
United StatesAdooq Bioscience
Toll Free: (866) 930-6790
Fax: +1-323-606-8156
Email: [email protected]
Not your Region? View all Distributors
Adooq Quality Guarantee
We promise all products perform as described.