Rucaparib (AG-014699) phosphate

AG-014699 (Rucaparib) is a PARP inhibitor that inhibits poly(ADP-ribose) polymerase (PARP) is a key enzyme in DNA repair.
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Rucaparib (AG-014699) phosphate 5mg
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Rucaparib (AG-014699) phosphate 25mg
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Rucaparib (AG-014699) phosphate 50mg
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Rucaparib (AG-014699) phosphate 100mg
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Rucaparib (AG-014699) phosphate 10mM * 1mL in DMSO
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Adooq Products cited in reputable paper
Adooq's Rucaparib (AG-014699) phosphate has been cited by 2 publications
  • Ali Divan, .et al. , Pharmacol Res Perspect, 2020, Apr; 8(2): e00586 PMID: 32342655
  • Tahira Baloch, .et al. , BMC Cancer, 2019, Jan 10;19(1):44 PMID: 30630446
  • Biological Activity
    Discription AG-014699 (Rucaparib) is a PARP inhibitor that inhibits poly(ADP-ribose) polymerase (PARP) is a key enzyme in DNA repair.
    Target Value
    Product Information
    Catalog Num A10045
    Formula C19H18FN3O.H3PO4
    Molecular Weight 421.4
    CAS Number 459868-92-9
    SMILES CNCC1=CC=C(C=C1)C2=C3CCNC(=O)C4=CC(=CC(=C34)N2)F.OP(=O)(O)O
    Synonyms PF-01367338,AG-014447 (as free base)

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    In vitro (25°C) DMSO 81 mg/mL (192.23 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 2% DMSO+30% PEG 300+2% Tween 80+ddH2O 9 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 23.73 mL 118.65 mL 237.3 mL
    0.5 mM 4.75 mL 23.73 mL 47.46 mL
    1 mM 2.37 mL 11.87 mL 23.73 mL
    5 mM 0.47 mL 2.37 mL 4.75 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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