AG14361

Catalog No.: A10046

PARP inhibitor

AG14361

AG14361 Chemical Structure

CAS NO. 328543-09-5

AG14361 is a potent PARP inhibitor, enhanced Temozolomide (TMZ) cytotoxicity in MMR(mismatch repair)-proficient / deficient cells.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $100.00

Special Price $80.00

10 mg

Regular Price: $170.00

Special Price $136.00

50 mg

Regular Price: $550.00

Special Price $440.00

100 mg

Regular Price: $900.00

Special Price $720.00

10mM * 1mL in DMSO
$123.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

AG14361 is a potent PARP inhibitor, enhanced Temozolomide (TMZ) cytotoxicity in MMR(mismatch repair)-proficient / deficient cells.
Targets
PARP1 (Cell-free assay)
<5 nM(Ki)
In vitro (25°C) DMSO 12 mg/mL (37.45 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.21 mL 156.05 mL 312.11 mL
0.5 mM 6.24 mL 31.21 mL 62.42 mL
1 mM 3.12 mL 15.61 mL 31.21 mL
5 mM 0.62 mL 3.12 mL 6.24 mL

*The above data is based on the productmolecular weight 320.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A10046
Actions Inhibitor
M. Wt 320.4
Formula C19H20N4O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 328543-09-5
Synonyms AG-14361
SMILES CN(C)CC1=CC=C(C=C1)C2=NC3=CC=CC4=C3N2CCNC4=O

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