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PARP inhibitor

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Catalog No. A10046

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
AG14361 5mg A10046-5

Regular Price: $100.00

Special Price: $90.00

AG14361 10mg A10046-10

Regular Price: $170.00

Special Price: $153.00

AG14361 50mg A10046-50

Regular Price: $550.00

Special Price: $495.00

AG14361 100mg A10046-100

Regular Price: $900.00

Special Price: $810.00

AG14361 10mM * 1mL in DMSO A10046-10mM-D

Regular Price: $123.00

Special Price: $110.70

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

AG14361 is a potent PARP inhibitor, enhanced Temozolomide (TMZ) cytotoxicity in MMR(mismatch repair)-proficient / deficient cells.


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Publications citing Adooq Products
AG14361  Citations (1)
  • Vimal Pandey, .et al. Roscovitine effectively enhances antitumor activity of temozolomide in vitro and in vivo mediated by increased autophagy and Caspase-3 dependent apoptosis, Scientific Reports, 2019, 9, Article number: 5012

Chemical Information

Catalog Num A10046
Actions Inhibitor
M. Wt 320.4
Formula C19H20N4O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 328543-09-5
Synonyms AG-14361

Biological Activity

AG14361 is a potent PARP inhibitor, enhanced Temozolomide (TMZ) cytotoxicity in MMR(mismatch repair)-proficient / deficient cells.
PARP1 (Cell-free assay)
<5 nM(Ki)


Solubility (25°C) * In vitro DMSO 12 mg/mL (37.45 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.21 mL 156.05 mL 312.11mL
0.5 mM 6.24 mL 31.21 mL 62.42 mL
1 mM 3.12 mL 15.61 mL 31.21 mL
5 mM 0.62 mL 3.12 mL 6.24 mL

*The above data is based on the productmolecular weight 320.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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