PJ 34 hydrochloride
PJ 34 hydrochloride is a potent inhibitor of poly(ADP-ribose) polymerase (PARP) (EC50 = 20 nM).
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Adooq Products cited in reputable paper
Adooq's PJ 34 hydrochloride has been cited by 2 publications
- Wigle TJ, .et al. , SLAS Discov, 2019, Dec 19:2472555219883623 PMID: 31855104
- Alvin Z.Lu, .et al. , Biochem Pharmacol, 2019, May 7. pii: S0006-2952(19)30171-6 PMID: 31075269
PJ 34 hydrochloride related products
Biological Activity
| Description | PJ 34 hydrochloride is a potent inhibitor of poly(ADP-ribose) polymerase (PARP) (EC50 = 20 nM). | ||
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Product Information
| Catalog Num | A12665 |
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| Formula | C17H17N3O2.HCl |
| Molecular Weight | 331.8 |
| CAS Number | 344458-15-7 |
| SMILES | CN(C)CC(=O)NC1=CC2=C(C=C1)NC(=O)C3=CC=CC=C32.Cl |
| Synonyms | PJ34, PJ-34 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro (25°C) | DMSO | 57 mg/mL (171.79 mM) | |
| Water | 57 mg/mL (171.79 mM) | ||
| Ethanol | Insoluble | ||
| In vivo | 30% PEG400+0.5% Tween80+5% propylene glycol | 14 mg/mL | |
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.14 mL | 150.69 mL | 301.39 mL |
| 0.5 mM | 6.03 mL | 30.14 mL | 60.28 mL |
| 1 mM | 3.01 mL | 15.07 mL | 30.14 mL |
| 5 mM | 0.6 mL | 3.01 mL | 6.03 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
