NU 1025

Catalog No.: A15375

PARP inhibitor

NU 1025

NU 1025 Chemical Structure

CAS NO. 90417-38-2

NU 1025 is a potent poly(ADP-ribose) polymerase (PARP) inhibitor, which potentiates the cytotoxicity of a panel of mechanistically diverse anti-cancer agents in L1210 cells.

Availability: In stock

Package Price Qty
5 mg
$80.00
25 mg
$250.00
50 mg
$480.00
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Biological Activity

NU 1025 is a potent poly(ADP-ribose) polymerase (PARP) inhibitor, which potentiates the cytotoxicity of a panel of mechanistically diverse anti-cancer agents in L1210 cells.
Targets
PARP
400 nM
In vitro (25°C) DMSO 34 mg/mL (192.99 mM)
Water Insoluble
Ethanol Warmed: 6 mg/mL
In vivo 40% PEG 400+saline 17 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 56.75 mL 283.77 mL 567.54 mL
0.5 mM 11.35 mL 56.75 mL 113.51 mL
1 mM 5.68 mL 28.38 mL 56.75 mL
5 mM 1.14 mL 5.68 mL 11.35 mL

*The above data is based on the productmolecular weight 176.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15375
Actions Inhibitor
CAS No. 90417-38-2
Formula C9H8N2O2
M. Wt 176.2
Purity >98%
Synonyms NU1025, NU-1025
SMILES CC1=NC(=O)C2=C(N1)C(=CC=C2)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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