Catalog No.
Product Name
Application
Product Information
Citations
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PROTAC linker
N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5 is a PEG-based linker designed for the synthesis of PROTACs, functioning primarily through click chemistry mechanisms. It features an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, this compound is capable of participating in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN moieties, making it useful for selective protein degradation studies and related applications in chemical biology. -
PROTAC linker
N-(m-PEG4)-N'-(azide-PEG4)-Cy7 is a PEG-based linker designed for use in PROTAC (proteolysis targeting chimeras) synthesis. This compound features an azide functional group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing partners, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. Its biological activity in forming stable linkages facilitates targeted proteolysis research applications, making it a valuable tool for molecular biology and drug development studies. -
PROTAC Linkers
Boc-N-Amido-PEG3-azide is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound features an azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with dibenzocyclooctyne (DBCO) or bicyclo[6.1.0]nonyne (BCN) groups, making it a versatile tool for chemical research and development in targeted protein degradation studies. -
PROTAC Linkers
Pyrene azide 3 is a PEG-based PROTAC linker designed for the synthesis of PROTACs. It features an azide group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-bearing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-containing compounds, making it versatile for targeted protein degradation applications in chemical biology research. -
PROTAC Linker
Boc-NHCH2CH2-PEG1-azide is a PEG-based linker specifically designed for use in synthesizing PROTACs (Proteolysis Targeting Chimeras). This compound features an azide group that enables it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with entities containing DBCO or BCN groups, facilitating the development of targeted protein degradation strategies in chemical research. -
PROTAC Linker
Boc-NH-PEG6-azide is a PEG-based linker designed for use in PROTAC (proteolysis-targeting chimera) synthesis. This compound features an azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, Boc-NH-PEG6-azide is capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) with constructs containing DBCO or BCN groups. Its applications are pivotal in the development of targeted protein degradation strategies. -
PROTAC Linkers
Boc-N-Amido-PEG2-C2-azide is a PEG-based PROTAC linker designed for the synthesis of targeted protein degradation agents. This compound contains an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-functionalized molecules, enhancing conjugation efficiency. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups, making it suitable for diverse bioconjugation applications in chemical biology and drug discovery. -
Biochemical Assay Reagent
Dodecyl azide (1-Azidododecane) is a biochemical assay reagent featuring an azide functional group linked to a 12-carbon alkyl chain. It demonstrates the ability to undergo click chemistry reactions, specifically with alkynes, BCN, and DBCO. This compound is valuable for applications in bioconjugation and labeling studies, enabling researchers to investigate various biological interactions and pathways. -
Biochemical Assay Reagent
(E,E,E)-Farnesyl alcohol azide is a versatile biochemical assay reagent that serves as a precursor for the synthesis of C15-Azide analogs. This compound plays a crucial role in various chemical biology applications, enabling researchers to study azide functionalization and facilitate click chemistry reactions. Its unique structure allows for incorporation into biomolecules, thus aiding in the investigation of protein labeling and modification techniques. -
PEG Derivative
Biotin-PEG10-azide is a PEG derivative featuring biotin, 10 polyethylene glycol units, and an azide moiety. The biotin component facilitates stable non-covalent interactions with streptavidin, while the azide functional group allows for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds. Additionally, the azide can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN derivatives. This reagent is suitable for diverse applications in bioconjugation, labeling, and biomolecule tracking in chemical biology research. -
Biotinylation Agent
Biotin-XX hydrazide is a carbonyl-reactive biotinylation agent designed to facilitate the conjugation of biotin to various biomolecules. Featuring two aminohexanoic acid spacers, this reagent enhances avidin-binding efficiency, making it an effective tool for a wide range of research applications, including protein labeling and immobilization studies. Its utility is critical for assays that require precise detection and quantification of biotinylated targets. -
PEG Derivative
Cholesterol-PEG3-azide is a PEG derivative that incorporates cholesterol, three polyethylene glycol (PEG) units, and an azide moiety. This compound participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules, as well as strain-promoted azide-alkyne cycloaddition (SPAAC) with entities bearing DBCO or BCN groups. It is valuable for bioconjugation applications, including the development of lipidated probes and drug delivery systems within biological research. -
Biochemical Assay Reagent
Biotin-PEG8-azide is a chemical reagent designed for click chemistry applications, enabling the biotinylation of macromolecules. This compound facilitates the selective labeling of proteins, nucleic acids, and other biomolecules, allowing for enhanced detection and purification in biochemical assays. Its utility in diverse research applications includes studying protein-protein interactions and tracing biological pathways. -
Glycobiology
2-Acetamido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-β-D-glucopyranosyl azide is a specialized biochemical reagent targeting glycobiology. This compound is instrumental in the study of glycan structure and function, facilitating research into carbohydrate chemistry, glycan synthesis and degradation, and protein-glycan interactions. Its applications are pivotal in advancing understanding in biomedicine and biotechnology, contributing to the exploration of the roles glycans play in biological systems. -
Cross-linking Agent
Mal-b-Lys(mal)-PEG4-amide-PEG3-azide is a versatile cross-linking agent that facilitates the conjugation of antibodies. This compound is particularly useful for the synthesis of antibody-drug conjugates (ADCs), enabling targeted delivery of therapeutic agents. Its unique structure allows for effective and selective cross-linking, making it valuable in various biochemical and biophysical research applications. -
Sugar
2,3,4,6-Tetra-O-acetyl-β-D-galactopyranosyl azide is a glycosyl azide derivative targeting glycobiology applications. This compound serves as a versatile substrate for the investigation of enzyme activity, facilitating research in carbohydrate biochemistry. Its high purity of 98% ensures reliable results in experimental settings. -
Biotin Derivative
Biotin N-(bromoacetyl)hydrazide is a biotin derivative that serves as a valuable tool for labeling and detecting biomolecules. This compound is instrumental in bioconjugation studies where it can facilitate the attachment of biotin to proteins, peptides, or other macromolecules. Its applications extend to various research fields, including proteomics, cellular imaging, and the development of biotin-affinity purification methods. -
Biochemical Assay Reagent
β-D-Glucopyranosyl azide, 2-(acetylamino)-2-deoxy, 3,4,6-triacetate is a biochemical assay reagent that serves as a versatile tool for glycosylation studies. It enables the exploration of glycosylation patterns and interactions in various biological systems. This compound is particularly useful in the development of glycoengineered therapeutics and for elucidating the roles of glycoconjugates in cellular processes. -
Biochemical Assay Reagent
Azide-C3-NHCO-C3-NHS ester serves as a versatile linker in biochemical assays, facilitating efficient and specific ligation through click chemistry. This reagent is ideal for applications in protein labeling, biomolecule modification, and the development of complex biochemical systems. Its reactive nature makes it a valuable tool for researchers engaged in chemical synthesis and functionalization studies. -
Biochemical Reagent
Pent-4-ynehydrazide is a biochemical reagent employed as an intermediate in organic synthesis. It serves as a valuable precursor for the synthesis of Hydrazone-DOX-Alkyne. This compound is particularly relevant in cancer research, facilitating the exploration of therapeutic applications and development of novel treatment strategies. -
Glycobiology
3,4,6-Tri-O-acetyl-2-deoxy-2-phthalimido-α-D-glucopyranosyl azide is a specialized reagent utilized in glycobiology, focusing on the study of carbohydrate structures and their biological significance. It facilitates research on glycan synthesis and recognition, contributing to the understanding of glycan-related processes in various biological systems. This compound is essential for investigating the roles of glycans in health and disease, making it a valuable tool for researchers in the fields of biomedicine and biotechnology. -
Glycobiology
Hepta-O-acetyl-β-lactosyl azide is a biochemical reagent that acts as a reliable substrate for glycosyltransferases in glycobiology research. This compound facilitates the study of glycan structure and function by enabling the synthesis and analysis of glycan-related biomolecules. Its applications extend to carbohydrate chemistry, enzymology, and the investigation of protein-glycan interactions, aiding in the understanding of the biological roles of glycans in various systems. -
Biochemical Assay Reagents
2,3,4,6-Tetra-O-acetyl-α-D-mannopyranosyl azide serves as a biochemical reagent in glycobiology research. This compound facilitates the study of carbohydrate chemistry, glycan synthesis and degradation, as well as protein-glycan interactions. Its application extends to essential areas in basic research, biomedicine, and biotechnology, enabling deeper exploration of the role of glycans in biological systems. -
Click Chemical Reagent
Biotin-azide (N-(3-Azidopropyl)biotinamide) serves as a versatile click chemical reagent featuring a terminal azide moiety. This compound facilitates the synthesis of biotinylated conjugates through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, Biotin-azide is capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with dibenzocyclooctyne (DBCO) or bicyclo[6.1.0]nonyne (BCN) functional groups. Its applications span various fields, including bioconjugation and visualization studies in chemical biology. -
Cross-Linked Peptide
Azide-A-DSBSO crosslinker is a homobifunctional, azide-labeled crosslinking reagent that targets lysine residues through an NHS ester reaction. This membrane-permeable and acid-cleavable compound is particularly useful in cross-linking mass spectrometry (XL-MS) to investigate protein-protein interactions. Its mass spectrometry-cleavable properties enable efficient analysis of cross-linked complexes, facilitating deeper insights into protein dynamics and interactions in biological systems. -
Click Chemistry Reagent
Cyclo[Arg-Gly-Asp-D-Phe-Lys(Azide)] is a click chemistry reagent featuring an azide functional group. This compound facilitates the efficient and specific labeling of biomolecules, including nucleic acids, lipids, and proteins, making it valuable in various research applications. Its properties allow for high-yield reactions and straightforward conjugation processes, enabling advancements in drug development, bioconjugation, and materials science. -
Long Chain Protein Modification Reagent
Biotin LC hydrazide is a long chain protein modification reagent that specifically targets periodate-oxidized glycoproteins. It facilitates the biotinylation of these proteins, enhancing their detection and isolation in various biological assays. This reagent is widely used in research applications that require the study of glycoprotein functionality and interactions. -
Azide
Cholesteryl-Teg azide is a cholesterol-modified azide that facilitates bioconjugation reactions. It serves as a valuable ligand for tagging and modifying biomolecules, particularly RNA strands, enabling advanced studies in molecular biology and drug development. Its properties support research in areas such as gene delivery and the synthesis of cholesterol-based therapeutics. -
Glycoconjugates Label
Biocytin hydrazide is a selective labeling reagent designed for targeting sialic acids, galactose, and other sugars in glycoconjugates through avidin-biotin technology. This compound facilitates the study of glycan structures and their biological roles, aiding in research applications such as glycoprotein analysis, cell surface marker identification, and carbohydrate-protein interactions. Its specificity makes it an invaluable tool for investigating complex carbohydrate moieties in various biological systems. -
Biochemical Assay Reagent
3-Chlorophenylacetylhydrazide functions as a biochemical assay reagent, essential for various life science research applications. This compound is utilized as a biological material, facilitating the study of hydrazine derivatives and their interactions in biochemical assays. Its properties make it valuable for exploring enzymatic activities and metabolic processes in cellular systems. -
Biochemical Assay Reagent
2,3,4,6-Tetra-O-acetyl-β-D-galactopyranosyl azide is a click chemistry reagent featuring an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) with alkyne-containing compounds, such as DBCO and BCN. This compound serves as a valuable biochemical assay reagent in various life science research applications, particularly in glycosylation studies and bioconjugation. Its stable acetylated form enhances solubility and reactivity, making it an effective tool for the synthesis of complex biomolecules and labeled substrates. -
PEG Derivative
Azide-PEG4-Desthiobiotin is a polyethylene glycol (PEG) derivative featuring an azide group and desthiobiotin. This reagent enables stable non-covalent interactions with streptavidin, facilitating applications in bioconjugation and biomolecular labeling. It is suitable for click chemistry, undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN moieties. -
Glycobiology
2-Acetamido-2-deoxy-β-D-glucopyranosyl azide is a biochemical reagent utilized in glycobiology to explore glycan structures and functions. It plays a critical role in studying carbohydrate chemistry, enzymatic processes involved in glycan formation and degradation, and protein-glycan interactions. This compound supports various research applications within basic biological research, biomedicine, and biotechnological advancements. -
Biochemical Reagent
11-Maleimidoundecanoic acid hydrazide is a biochemical reagent characterized by its maleimide group, which facilitates selective covalent conjugation to thiol-containing biomolecules. This compound is primarily utilized in bioconjugation applications, enabling the development of targeted therapeutics and diagnostic tools. Its ability to form stable linkages with proteins and peptides makes it a valuable resource for researchers studying protein interactions and creating antibody conjugates. -
Biochemical Assay Reagent
Azide-PEG5-Ms is a PEG-based linker designed for use in biochemical assays, featuring an azide group that undergoes Click Chemistry with BCN, DBCO, and alkynes. The mesyl group serves as an effective leaving group for nucleophilic substitution reactions, enhancing the versatility of this reagent. The polyethylene glycol (PEG) spacer provides improved water solubility, making it suitable for a variety of biological applications, including bioconjugation and drug delivery studies. -
Biochemical Assay Reagent
Azido-PEG1-hydrazide hydrochloride is a bifunctional polyethylene glycol linker featuring both azide and hydrazide groups. The azide portion facilitates reactions with alkyne, BCN, and DBCO through Click Chemistry, allowing the formation of stable triazole linkages. Meanwhile, the hydrazine moiety can react with aldehydes to produce semi-permanent hydrazone bonds. This reagent is valuable for biochemical assays and in the development of bioconjugates, enhancing the versatility of molecular modifications in research applications. -
Crosslinking Agent
Oxalyldihydrazide is a crosslinking agent that effectively captures carbonylated proteins, making it an essential tool in proteomics research. Its ability to form stable linkages allows for the precise analysis of protein modifications on microchips, facilitating the study of protein interactions and functions. Researchers utilize oxalyldihydrazide to enhance the detection and characterization of biomolecules in diverse applications, including disease biomarker discovery and cellular pathway analysis. -
Benzothiadiazine Diuretic
Cyclopenthiazide is a benzothiadiazine diuretic that acts by inhibiting the reabsorption of sodium chloride and water in the distal renal tubules. This mechanism leads to increased renal excretion and antihypertensive effects. It is commonly utilized in research to study diuretic actions and their impact on blood pressure regulation. -
Non-natural Amino Acid
(Rac)-Azide-phenylalanine is a non-natural amino acid featuring an azide functional group, allowing for selective incorporation into proteins for labeling purposes. This compound serves as a valuable tool in click chemistry, participating in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules. Its applications extend to bioconjugation strategies, facilitating the study of protein interactions and dynamics in chemical biology and biochemical research. -
PROTAC Linker
5-(Biotinamido)pentylazide is a versatile PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). This reagent features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkynes. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN moieties, making it a valuable tool for chemical research in targeted protein degradation and related applications. -
PROTAC Linkers
m-PEG8-azide is a PEG-based linker specifically designed for PROTAC synthesis. This compound features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, m-PEG8-azide is suitable for strain-promoted alkyne-azide cycloaddition (SPAAC) when used with DBCO or BCN groups. Its versatile reactivity makes it a valuable tool for researchers engaged in targeted protein degradation studies. -
PROTAC Linker
Azide-PEG3-C1-Ala is a PEG-based linker designed for PROTAC (proteolysis-targeting chimera) synthesis. This compound features an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with dibenzocyclooctyne (DBCO) or bicyclononyne (BCN) compounds. This versatile linker is essential for studying targeted protein degradation and enhancing the efficacy of therapeutic agents. -
PROTAC Linker
Amino-PEG8-hydrazide-Boc is a PEG-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). Its primary mechanism targets the recruitment of E3 ubiquitin ligases, facilitating the ubiquitination and degradation of specific proteins. This reagent is essential for developing novel therapeutic strategies aimed at modulating protein levels and has significant applications in chemical biology and drug discovery research. -
PROTAC Linkers
Propargyl-PEG3-azide is a PEG-based linker specifically designed for the synthesis of PROTACs. This compound features an azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it is capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-functionalized compounds. Its versatility makes it a valuable tool in chemical biology and therapeutic research applications involving targeted protein degradation. -
PROTAC linker
N-methyl-N'-(azide-PEG3)-Cy3 is a PEG-based linker designed for use in the synthesis of PROTACs, facilitating targeted protein degradation. This compound acts as a click chemistry reagent due to the presence of an azide group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN functionalized compounds, making it a versatile tool in chemical biology and medicinal chemistry research applications. -
PROTAC linker
N-(azide-PEG3)-N'-(Amine-C3-Amide-PEG4)-Cy5 is a PEG-based linker designed for the synthesis of PROTACs, functioning primarily through the azide group. This compound participates in click chemistry, specifically through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. It is also capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN functionalized entities, making it a versatile tool for targeted protein degradation studies and other bioconjugation applications. -
PROTAC Linker
Azide-PEG5-Boc is a PEG-based linker designed for use in the synthesis of PROTACs, functioning primarily as a click chemistry reagent. Its azide group enables efficient copper-catalyzed azide-alkyne cycloaddition reactions with alkyne-containing compounds, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-functionalized molecules. This versatility makes Azide-PEG5-Boc a valuable tool in the development of targeted protein degradation strategies in chemical biology research. -
PROTAC linker
N-Boc-N-bis(C2-PEG1-azide) is a PROTAC linker designed to facilitate the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features an azide functional group that enables it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAC) when paired with alkyne-containing moieties. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN functionalized molecules, providing versatile coupling options for bioconjugation and targeting studies in chemical biology. -
PROTAC linker
Boc-Aminooxy-PEG4-azide is a PEG-based PROTAC linker that facilitates the synthesis of PROTACs through its unique azide functionality. This compound participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN moieties. Its versatile click chemistry capabilities make it an essential tool for researchers studying targeted protein degradation and other innovative therapeutic approaches. -
PROTAC Linker
Methyltetrazine-Ph-PEG4-azide is a PEG-based linker specifically designed for the synthesis of PROTACs, functioning as a vital component in targeted protein degradation strategies. This compound features a Tetrazine moiety that enables inverse electron-demand Diels-Alder reactions (iEDDA) with TCO-containing partners, enhancing the efficiency of linkage in complex biomolecular assemblies. Additionally, the azide functionality facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) and can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN derivatives. This dual reactivity expands its utility in bioconjugation and chemical biology applications.
