Azide-PEG3-Sulfone-PEG3-azide is a PEG-based linker designed for use in PROTAC synthesis, facilitating the creation of targeted protein degraders. This compound features an azide functional group, enabling it to engage in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it is capable of participating in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups, making it versatile for various bioconjugation applications in chemical research.
Azide-PEG3-Sulfone-PEG3-azide is a PEG-based linker designed for use in PROTAC synthesis, facilitating the creation of targeted protein degraders. This compound features an azide functional group, enabling it to engage in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it is capable of participating in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups, making it versatile for various bioconjugation applications in chemical research.
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